Insufficient scRNA-seq data for expression of ILDR1 at single-cell level.
Insufficient scRNA-seq data for expression of ILDR1 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
pancreas | 100% | 358.95 | 328 / 328 | 94% | 16.11 | 168 / 178 |
thymus | 100% | 419.28 | 653 / 653 | 91% | 24.42 | 549 / 605 |
prostate | 88% | 301.47 | 216 / 245 | 99% | 29.37 | 498 / 502 |
kidney | 100% | 525.44 | 89 / 89 | 79% | 14.70 | 708 / 901 |
lung | 83% | 179.49 | 479 / 578 | 94% | 17.18 | 1083 / 1155 |
breast | 57% | 136.41 | 263 / 459 | 95% | 17.67 | 1060 / 1118 |
intestine | 49% | 275.17 | 470 / 966 | 95% | 16.83 | 500 / 527 |
bladder | 48% | 226.19 | 10 / 21 | 85% | 13.84 | 428 / 504 |
esophagus | 38% | 156.96 | 555 / 1445 | 86% | 12.92 | 157 / 183 |
ureter | 0% | 0 | 0 / 0 | 100% | 11.82 | 1 / 1 |
ovary | 1% | 0.66 | 2 / 180 | 98% | 18.77 | 422 / 430 |
stomach | 4% | 2.48 | 14 / 359 | 88% | 14.23 | 252 / 286 |
tonsil | 0% | 0 | 0 / 0 | 87% | 22.88 | 39 / 45 |
uterus | 11% | 24.25 | 18 / 170 | 75% | 13.44 | 342 / 459 |
spleen | 84% | 77.13 | 202 / 241 | 0% | 0 | 0 / 0 |
skin | 66% | 87.46 | 1194 / 1809 | 1% | 0.06 | 5 / 472 |
adrenal gland | 66% | 85.71 | 170 / 258 | 1% | 0.05 | 2 / 230 |
lymph node | 0% | 0 | 0 / 0 | 45% | 4.94 | 13 / 29 |
liver | 4% | 2.71 | 10 / 226 | 24% | 3.09 | 96 / 406 |
peripheral blood | 20% | 216.29 | 184 / 929 | 0% | 0 | 0 / 0 |
adipose | 1% | 0.88 | 11 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 1% | 0.47 | 9 / 1335 | 0% | 0 | 0 / 0 |
heart | 0% | 0.18 | 2 / 861 | 0% | 0 | 0 / 0 |
muscle | 0% | 0.07 | 1 / 803 | 0% | 0 | 0 / 0 |
brain | 0% | 0.04 | 2 / 2642 | 0% | 0 | 0 / 705 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0010669 | Biological process | epithelial structure maintenance |
GO_0070542 | Biological process | response to fatty acid |
GO_1990830 | Biological process | cellular response to leukemia inhibitory factor |
GO_0090277 | Biological process | positive regulation of peptide hormone secretion |
GO_0051649 | Biological process | establishment of localization in cell |
GO_0061833 | Biological process | protein localization to tricellular tight junction |
GO_0016192 | Biological process | vesicle-mediated transport |
GO_1904274 | Biological process | tricellular tight junction assembly |
GO_0030072 | Biological process | peptide hormone secretion |
GO_0043484 | Biological process | regulation of RNA splicing |
GO_0070160 | Cellular component | tight junction |
GO_0005886 | Cellular component | plasma membrane |
GO_0032991 | Cellular component | protein-containing complex |
GO_0005829 | Cellular component | cytosol |
GO_0005923 | Cellular component | bicellular tight junction |
GO_0061689 | Cellular component | tricellular tight junction |
GO_0042802 | Molecular function | identical protein binding |
GO_0070506 | Molecular function | high-density lipoprotein particle receptor activity |
GO_0005515 | Molecular function | protein binding |
Gene name | ILDR1 |
Protein name | Immunoglobulin-like domain-containing receptor 1 (Angulin-2) |
Synonyms | |
Description | FUNCTION: Maintains epithelial barrier function by recruiting MARVELD2/tricellulin to tricellular tight junctions (tTJs) . Crucial for normal hearing by maintaining the structural and functional integrity of tTJs, which are critical for the survival of auditory neurosensory HCs. Mediates fatty acids and lipoproteins-stimulated CCK/cholecystokinin secretion in the small intestine. In the inner ear, may regulate alternative pre-mRNA splicing via binding to TRA2A, TRA2B and SRSF1 (By similarity). .; FUNCTION: (Microbial infection) Promotes influenza virus infection by inhibiting viral nucleoprotein NP binding to PLSCR1 and thereby PLSCR1-mediated antiviral activity. . |
Accessions | ENST00000273691.7 [Q86SU0-2] ENST00000393631.5 [Q86SU0-5] ENST00000642615.1 [Q86SU0-3] ENST00000344209.10 [Q86SU0-1] Q86SU0 |