IGSF1 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of IGSF1 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of IGSF1 at tissue level.

III. Associated gene sets

GO_0006355Biological processregulation of DNA-templated transcription
GO_0032926Biological processnegative regulation of activin receptor signaling pathway
GO_0002764Biological processimmune response-regulating signaling pathway
GO_0005576Cellular componentextracellular region
GO_0016020Cellular componentmembrane
GO_0038102Molecular functionactivin receptor antagonist activity
GO_0005515Molecular functionprotein binding
GO_0034711Molecular functioninhibin binding

IV. Literature review

[source]
Gene nameIGSF1
Protein nameImmunoglobulin superfamily member 1
Immunoglobulin superfamily member 1 (IgSF1) (Immunoglobulin-like domain-containing protein 1) (Inhibin-binding protein) (InhBP) (Pituitary gland-specific factor 2) (p120)
SynonymsIGDC1
KIAA0364
PGSF2
DescriptionFUNCTION: Seems to be a coreceptor in inhibin signaling, but seems not to be a high-affinity inhibin receptor. Antagonizes activin A signaling in the presence or absence of inhibin B (By similarity). Necessary to mediate a specific antagonistic effect of inhibin B on activin-stimulated transcription. .

AccessionsQ8N6C5
ENST00000650945.1
ENST00000370900.5 [Q8N6C5-3]
ENST00000370901.4 [Q8N6C5-3]
A0A494C0K8
ENST00000361420.8 [Q8N6C5-1]
A0A494C0W8
ENST00000370910.5 [Q8N6C5-2]
ENST00000651402.1
A0A494C0E7
A0A494C0H8
ENST00000650730.1
ENST00000370903.8 [Q8N6C5-4]
ENST00000370904.6 [Q8N6C5-2]
ENST00000651556.1 [Q8N6C5-1]
ENST00000652189.1