IGFBPL1 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of IGFBPL1 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of IGFBPL1 at tissue level.

III. Associated gene sets

GO_0071228Biological processcellular response to tumor cell
GO_0009966Biological processregulation of signal transduction
GO_0001558Biological processregulation of cell growth
GO_0005615Cellular componentextracellular space
GO_0062023Cellular componentcollagen-containing extracellular matrix
GO_0005520Molecular functioninsulin-like growth factor binding
GO_0003674Molecular functionmolecular_function

IV. Literature review

[source]
Gene nameIGFBPL1
Protein nameInsulin-like growth factor-binding protein-like 1 (IGFBP-related protein 10) (Insulin-like growth factor-binding-related protein 4) (IGFBP-rP4)
Insulin-like growth factor binding protein-like 1
SynonymsIGFBPRP4
DescriptionFUNCTION: IGF-binding proteins prolong the half-life of IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs in cell culture. They alter the interaction of IGFs with their cell surface receptors (By similarity). May be a putative tumor suppressor protein. .

AccessionsQ8WX77
A0A286RQC1
ENST00000377694.2