I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| epithelial cell | 4 studies | 32% ± 9% | |
| basal cell | 4 studies | 26% ± 7% | |
| endothelial cell | 3 studies | 24% ± 5% | |
| fibroblast | 3 studies | 21% ± 6% | |
| erythrocyte | 3 studies | 32% ± 12% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| epithelial cell | 4 studies | 32% ± 9% | |
| basal cell | 4 studies | 26% ± 7% | |
| endothelial cell | 3 studies | 24% ± 5% | |
| fibroblast | 3 studies | 21% ± 6% | |
| erythrocyte | 3 studies | 32% ± 12% |
Insufficient scRNA-seq data for expression of IFRD2 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 100% | 2687.17 | 1445 / 1445 | 100% | 33.56 | 183 / 183 |
| ovary | 100% | 1665.18 | 180 / 180 | 100% | 38.48 | 430 / 430 |
| prostate | 100% | 3195.37 | 245 / 245 | 100% | 53.19 | 500 / 502 |
| liver | 100% | 3152.64 | 226 / 226 | 100% | 37.72 | 404 / 406 |
| intestine | 100% | 2399.18 | 966 / 966 | 99% | 64.95 | 524 / 527 |
| stomach | 100% | 3486.70 | 359 / 359 | 99% | 54.25 | 284 / 286 |
| skin | 100% | 2384.12 | 1807 / 1809 | 99% | 45.47 | 469 / 472 |
| thymus | 100% | 2525.23 | 653 / 653 | 99% | 35.60 | 600 / 605 |
| breast | 100% | 2605.89 | 459 / 459 | 99% | 31.87 | 1108 / 1118 |
| uterus | 100% | 2136.36 | 170 / 170 | 99% | 39.57 | 454 / 459 |
| pancreas | 100% | 3139.23 | 328 / 328 | 99% | 35.21 | 176 / 178 |
| bladder | 100% | 2490.24 | 21 / 21 | 99% | 49.85 | 498 / 504 |
| lung | 99% | 2433.61 | 575 / 578 | 99% | 34.97 | 1144 / 1155 |
| kidney | 100% | 2124.28 | 89 / 89 | 98% | 23.97 | 884 / 901 |
| adrenal gland | 100% | 2832.22 | 258 / 258 | 94% | 20.06 | 216 / 230 |
| brain | 87% | 700.92 | 2287 / 2642 | 100% | 21.42 | 702 / 705 |
| adipose | 100% | 2502.60 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 40.50 | 29 / 29 |
| muscle | 100% | 5107.61 | 803 / 803 | 0% | 0 | 0 / 0 |
| spleen | 100% | 1971.13 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 34.27 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 33.40 | 1 / 1 |
| blood vessel | 100% | 1935.24 | 1332 / 1335 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 99% | 26.52 | 79 / 80 |
| heart | 98% | 2300.13 | 847 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 65% | 942.63 | 601 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0017148 | Biological process | negative regulation of translation |
| GO_0005634 | Cellular component | nucleus |
| GO_0043022 | Molecular function | ribosome binding |
| GO_0030371 | Molecular function | translation repressor activity |
| GO_0005515 | Molecular function | protein binding |
| Gene name | IFRD2 |
| Protein name | Interferon-related developmental regulator 2 (Protein SKMC15) Interferon related developmental regulator 2 |
| Synonyms | |
| Description | FUNCTION: Ribosome-binding protein that acts as an inhibitor of mRNA translation by promoting ribosome inactivation . Associates with the P- and E-sites of the ribosome and inserts a C-terminal helix into the mRNA exit channel to preclude translation (By similarity). . |
| Accessions | ENST00000426499.5 ENST00000417626.8 Q12894 F8WEI6 H7C444 ENST00000414734.5 ENST00000438296.1 ENST00000436390.5 H7C2Z4 |
