IARS2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0106074Biological processaminoacyl-tRNA metabolism involved in translational fidelity
GO_0006428Biological processisoleucyl-tRNA aminoacylation
GO_0006418Biological processtRNA aminoacylation for protein translation
GO_0032543Biological processmitochondrial translation
GO_0005759Cellular componentmitochondrial matrix
GO_0005739Cellular componentmitochondrion
GO_0000049Molecular functiontRNA binding
GO_0004822Molecular functionisoleucine-tRNA ligase activity
GO_0002161Molecular functionaminoacyl-tRNA editing activity
GO_0005524Molecular functionATP binding

IV. Literature review

[source]
Gene nameIARS2
Protein nameAlternative protein IARS2
Isoleucine--tRNA ligase, mitochondrial (EC 6.1.1.5) (Isoleucyl-tRNA synthetase) (IleRS)
Synonyms
DescriptionFUNCTION: Aminoacyl-tRNA synthetase that catalyzes the specific attachment of isoleucine to its cognate tRNA (tRNA(Ile)). .

AccessionsL8EA13
Q9NSE4
ENST00000366922.3
L8E8E9