Name | Number of supported studies | Average coverage | |
---|---|---|---|
brush cell | 4 studies | 48% ± 17% |
Insufficient scRNA-seq data for expression of HTR3E at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
intestine | 64% | 30.93 | 622 / 966 | 6% | 0.14 | 31 / 527 |
stomach | 49% | 2.57 | 175 / 359 | 5% | 0.14 | 15 / 286 |
prostate | 50% | 2.59 | 123 / 245 | 1% | 0.02 | 4 / 502 |
lung | 38% | 1.78 | 222 / 578 | 2% | 0.13 | 27 / 1155 |
pancreas | 30% | 1.09 | 98 / 328 | 10% | 0.26 | 18 / 178 |
bladder | 24% | 0.67 | 5 / 21 | 4% | 0.22 | 22 / 504 |
brain | 25% | 0.84 | 655 / 2642 | 0% | 0 | 0 / 705 |
uterus | 20% | 0.59 | 34 / 170 | 4% | 0.64 | 19 / 459 |
ovary | 19% | 0.56 | 35 / 180 | 0% | 0.01 | 2 / 430 |
thymus | 16% | 0.44 | 106 / 653 | 1% | 0.06 | 7 / 605 |
esophagus | 10% | 0.31 | 149 / 1445 | 4% | 0.10 | 8 / 183 |
breast | 13% | 0.37 | 61 / 459 | 0% | 0.00 | 3 / 1118 |
adrenal gland | 10% | 0.29 | 27 / 258 | 0% | 0 | 0 / 230 |
skin | 10% | 0.29 | 184 / 1809 | 0% | 0.00 | 1 / 472 |
muscle | 10% | 0.31 | 83 / 803 | 0% | 0 | 0 / 0 |
spleen | 10% | 0.22 | 23 / 241 | 0% | 0 | 0 / 0 |
kidney | 7% | 0.16 | 6 / 89 | 1% | 0.04 | 10 / 901 |
blood vessel | 8% | 0.18 | 101 / 1335 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 7% | 0.14 | 3 / 45 |
peripheral blood | 6% | 0.14 | 53 / 929 | 0% | 0 | 0 / 0 |
heart | 6% | 0.14 | 48 / 861 | 0% | 0 | 0 / 0 |
adipose | 5% | 0.13 | 66 / 1204 | 0% | 0 | 0 / 0 |
liver | 5% | 0.12 | 12 / 226 | 0% | 0 | 0 / 406 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0034220 | Biological process | monoatomic ion transmembrane transport |
GO_0042391 | Biological process | regulation of membrane potential |
GO_0007268 | Biological process | chemical synaptic transmission |
GO_0007210 | Biological process | serotonin receptor signaling pathway |
GO_0098662 | Biological process | inorganic cation transmembrane transport |
GO_0060079 | Biological process | excitatory postsynaptic potential |
GO_1902495 | Cellular component | transmembrane transporter complex |
GO_0045211 | Cellular component | postsynaptic membrane |
GO_1904602 | Cellular component | serotonin-activated cation-selective channel complex |
GO_0045202 | Cellular component | synapse |
GO_0005886 | Cellular component | plasma membrane |
GO_0043005 | Cellular component | neuron projection |
GO_0005231 | Molecular function | excitatory extracellular ligand-gated monoatomic ion channel activity |
GO_1904315 | Molecular function | transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential |
GO_0022850 | Molecular function | serotonin-gated monoatomic cation channel activity |
Gene name | HTR3E |
Protein name | 5-hydroxytryptamine receptor 3E (5-HT3-E) (5-HT3E) (Serotonin receptor 3E) 5-hydroxytryptamine receptor 3E |
Synonyms | |
Description | FUNCTION: Forms serotonin (5-hydroxytryptamine/5-HT3)-activated cation-selective channel complexes, which when activated cause fast, depolarizing responses in neurons. . |
Accessions | A5X5Y0 ENST00000436361.6 [A5X5Y0-4] ENST00000440596.2 [A5X5Y0-6] ENST00000335304.6 [A5X5Y0-3] C9J420 ENST00000431041.5 ENST00000415389.6 [A5X5Y0-1] ENST00000425359.6 [A5X5Y0-2] |