Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| epithelial cell of proximal tubule | 6 studies | 27% ± 8% | |
| astrocyte | 4 studies | 25% ± 4% | |
| epithelial cell | 3 studies | 29% ± 10% | |
| macrophage | 3 studies | 22% ± 3% | |
| glutamatergic neuron | 3 studies | 20% ± 2% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| pancreas | 3 studies | 19% ± 3% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 100% | 1238.19 | 2640 / 2642 | 100% | 82.84 | 704 / 705 |
| adrenal gland | 100% | 1851.22 | 258 / 258 | 97% | 103.11 | 222 / 230 |
| thymus | 100% | 1330.85 | 653 / 653 | 95% | 89.95 | 575 / 605 |
| prostate | 99% | 769.49 | 243 / 245 | 94% | 48.34 | 474 / 502 |
| ovary | 100% | 2590.64 | 180 / 180 | 93% | 60.78 | 399 / 430 |
| kidney | 100% | 2054.92 | 89 / 89 | 88% | 86.30 | 789 / 901 |
| lung | 99% | 702.61 | 571 / 578 | 70% | 28.95 | 813 / 1155 |
| breast | 96% | 592.90 | 441 / 459 | 71% | 25.67 | 799 / 1118 |
| skin | 71% | 264.90 | 1279 / 1809 | 91% | 83.49 | 429 / 472 |
| bladder | 100% | 837.29 | 21 / 21 | 59% | 34.84 | 299 / 504 |
| liver | 90% | 1870.02 | 204 / 226 | 67% | 75.23 | 273 / 406 |
| uterus | 99% | 1511.35 | 169 / 170 | 47% | 22.32 | 218 / 459 |
| intestine | 92% | 453.60 | 889 / 966 | 22% | 5.40 | 117 / 527 |
| eye | 0% | 0 | 0 / 0 | 100% | 376.78 | 80 / 80 |
| ureter | 0% | 0 | 0 / 0 | 100% | 40.76 | 1 / 1 |
| blood vessel | 99% | 676.03 | 1315 / 1335 | 0% | 0 | 0 / 0 |
| spleen | 98% | 424.74 | 237 / 241 | 0% | 0 | 0 / 0 |
| esophagus | 79% | 405.70 | 1147 / 1445 | 19% | 5.27 | 34 / 183 |
| lymph node | 0% | 0 | 0 / 0 | 97% | 38.95 | 28 / 29 |
| adipose | 94% | 430.86 | 1129 / 1204 | 0% | 0 | 0 / 0 |
| pancreas | 10% | 21.23 | 32 / 328 | 81% | 31.80 | 145 / 178 |
| stomach | 61% | 333.18 | 220 / 359 | 28% | 8.42 | 81 / 286 |
| heart | 45% | 136.48 | 385 / 861 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 31% | 6.14 | 14 / 45 |
| peripheral blood | 13% | 54.57 | 125 / 929 | 0% | 0 | 0 / 0 |
| muscle | 2% | 3.92 | 15 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0006706 | Biological process | steroid catabolic process |
| GO_0005829 | Cellular component | cytosol |
| GO_0047045 | Molecular function | testosterone 17-beta-dehydrogenase (NADP+) activity |
| GO_0004303 | Molecular function | estradiol 17-beta-dehydrogenase [NAD(P)+] activity |
| GO_0042802 | Molecular function | identical protein binding |
| GO_0005515 | Molecular function | protein binding |
| Gene name | HSD17B14 |
| Protein name | Hydroxysteroid 17-beta dehydrogenase 14 17-beta-hydroxysteroid dehydrogenase 14 (17-beta-HSD 14) (EC 1.1.1.62) (17-beta-hydroxysteroid dehydrogenase DHRS10) (Dehydrogenase/reductase SDR family member 10) (Retinal short-chain dehydrogenase/reductase retSDR3) (Short chain dehydrogenase/reductase family 47C member 1) |
| Synonyms | UNQ502/PRO474 SDR47C1 DHRS10 SDR3 |
| Description | FUNCTION: Has NAD-dependent 17-beta-hydroxysteroid dehydrogenase activity. Converts oestradiol to oestrone. The physiological substrate is not known. Acts on oestradiol and 5-androstene-3-beta,17-beta-diol (in vitro). . |
| Accessions | M0R147 ENST00000599157.5 M0R2R3 ENST00000263278.9 ENST00000596349.5 M0QY35 ENST00000595764.1 Q9BPX1 |
