HROB report

I. Expression across cell types

Insufficient scRNA-seq data for expression of HROB at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of HROB at tissue level.

III. Associated gene sets

GO_0000725Biological processrecombinational repair
GO_0006974Biological processDNA damage response
GO_0048232Biological processmale gamete generation
GO_0036297Biological processinterstrand cross-link repair
GO_0000731Biological processDNA synthesis involved in DNA repair
GO_0007292Biological processfemale gamete generation
GO_0090734Cellular componentsite of DNA damage
GO_0005634Cellular componentnucleus
GO_0005515Molecular functionprotein binding
GO_0003697Molecular functionsingle-stranded DNA binding

IV. Literature review

[source]
Gene nameHROB
Protein nameHomologous recombination OB-fold protein
SynonymsC17orf53
DescriptionFUNCTION: DNA-binding protein involved in homologous recombination that acts by recruiting the MCM8-MCM9 helicase complex to sites of DNA damage to promote DNA repair synthesis. .

AccessionsENST00000319977.8 [Q8N3J3-1]
ENST00000585683.6 [Q8N3J3-4]
Q8N3J3
ENST00000245382.6 [Q8N3J3-3]