Insufficient scRNA-seq data for expression of HROB at single-cell level.
Insufficient scRNA-seq data for expression of HROB at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
skin | 100% | 272.93 | 1806 / 1809 | 97% | 8.36 | 459 / 472 |
bladder | 100% | 89.48 | 21 / 21 | 97% | 10.75 | 488 / 504 |
uterus | 97% | 104.43 | 165 / 170 | 99% | 16.67 | 456 / 459 |
breast | 100% | 205.74 | 457 / 459 | 96% | 6.69 | 1078 / 1118 |
ovary | 97% | 106.63 | 175 / 180 | 99% | 9.76 | 424 / 430 |
esophagus | 96% | 248.14 | 1384 / 1445 | 99% | 13.10 | 182 / 183 |
intestine | 93% | 103.38 | 902 / 966 | 96% | 8.23 | 506 / 527 |
lung | 89% | 91.78 | 517 / 578 | 92% | 10.58 | 1066 / 1155 |
stomach | 72% | 67.56 | 257 / 359 | 96% | 8.27 | 275 / 286 |
brain | 51% | 35.25 | 1354 / 2642 | 68% | 3.42 | 478 / 705 |
liver | 59% | 37.50 | 133 / 226 | 57% | 3.15 | 230 / 406 |
adrenal gland | 85% | 61.13 | 220 / 258 | 27% | 1.25 | 63 / 230 |
prostate | 98% | 105.92 | 239 / 245 | 13% | 0.48 | 67 / 502 |
thymus | 77% | 46.66 | 504 / 653 | 33% | 1.79 | 198 / 605 |
pancreas | 27% | 14.81 | 89 / 328 | 78% | 3.70 | 139 / 178 |
kidney | 57% | 46.72 | 51 / 89 | 48% | 1.72 | 431 / 901 |
lymph node | 0% | 0 | 0 / 0 | 100% | 11.38 | 29 / 29 |
spleen | 100% | 176.68 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 20.44 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 6.08 | 1 / 1 |
adipose | 99% | 191.74 | 1196 / 1204 | 0% | 0 | 0 / 0 |
peripheral blood | 85% | 398.47 | 789 / 929 | 0% | 0 | 0 / 0 |
heart | 75% | 57.63 | 645 / 861 | 0% | 0 | 0 / 0 |
blood vessel | 68% | 46.16 | 904 / 1335 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 66% | 2.12 | 53 / 80 |
muscle | 60% | 69.21 | 479 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0000725 | Biological process | recombinational repair |
GO_0006974 | Biological process | DNA damage response |
GO_0048232 | Biological process | male gamete generation |
GO_0036297 | Biological process | interstrand cross-link repair |
GO_0000731 | Biological process | DNA synthesis involved in DNA repair |
GO_0007292 | Biological process | female gamete generation |
GO_0090734 | Cellular component | site of DNA damage |
GO_0005634 | Cellular component | nucleus |
GO_0005515 | Molecular function | protein binding |
GO_0003697 | Molecular function | single-stranded DNA binding |
Gene name | HROB |
Protein name | Homologous recombination OB-fold protein |
Synonyms | C17orf53 |
Description | FUNCTION: DNA-binding protein involved in homologous recombination that acts by recruiting the MCM8-MCM9 helicase complex to sites of DNA damage to promote DNA repair synthesis. . |
Accessions | ENST00000319977.8 [Q8N3J3-1] ENST00000585683.6 [Q8N3J3-4] Q8N3J3 ENST00000245382.6 [Q8N3J3-3] |