Insufficient scRNA-seq data for expression of HRC at tissue level.
Tissue | GTEx Coverage  | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| thymus | 79% | 525.99 | 518 / 653 | 78% | 3.11 | 472 / 605 |
| breast | 75% | 587.34 | 346 / 459 | 59% | 1.60 | 664 / 1118 |
| prostate | 30% | 268.64 | 74 / 245 | 91% | 3.82 | 457 / 502 |
| kidney | 33% | 237.01 | 29 / 89 | 77% | 6.90 | 697 / 901 |
| adrenal gland | 18% | 103.46 | 47 / 258 | 90% | 5.09 | 207 / 230 |
| uterus | 79% | 699.51 | 134 / 170 | 25% | 7.84 | 116 / 459 |
| heart | 100% | 39334.84 | 861 / 861 | 0% | 0 | 0 / 0 |
| muscle | 100% | 24863.51 | 803 / 803 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 100% | 2.78 | 1 / 1 |
| brain | 4% | 19.54 | 108 / 2642 | 93% | 2.36 | 656 / 705 |
| adipose | 87% | 875.79 | 1051 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 80% | 1279.87 | 1074 / 1335 | 0% | 0 | 0 / 0 |
| liver | 1% | 9.26 | 3 / 226 | 62% | 1.52 | 253 / 406 |
| bladder | 33% | 225.33 | 7 / 21 | 28% | 0.96 | 140 / 504 |
| pancreas | 0% | 2.20 | 1 / 328 | 56% | 1.08 | 100 / 178 |
| ovary | 44% | 377.43 | 80 / 180 | 12% | 0.39 | 50 / 430 |
| lung | 23% | 167.74 | 131 / 578 | 31% | 0.76 | 359 / 1155 |
| eye | 0% | 0 | 0 / 0 | 48% | 0.89 | 38 / 80 |
| esophagus | 32% | 184.46 | 457 / 1445 | 13% | 0.22 | 24 / 183 |
| skin | 13% | 85.19 | 228 / 1809 | 29% | 2.25 | 136 / 472 |
| intestine | 21% | 122.06 | 203 / 966 | 18% | 0.40 | 97 / 527 |
| stomach | 9% | 46.68 | 33 / 359 | 26% | 0.67 | 74 / 286 |
| tonsil | 0% | 0 | 0 / 0 | 22% | 1.79 | 10 / 45 |
| lymph node | 0% | 0 | 0 / 0 | 3% | 0.06 | 1 / 29 |
| peripheral blood | 2% | 14.45 | 15 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spleen | 0% | 0 | 0 / 241 | 0% | 0 | 0 / 0 |
| GO_0051480 | Biological process | regulation of cytosolic calcium ion concentration |
| GO_0033135 | Biological process | regulation of peptidyl-serine phosphorylation |
| GO_0002027 | Biological process | regulation of heart rate |
| GO_0006936 | Biological process | muscle contraction |
| GO_1903169 | Biological process | regulation of calcium ion transmembrane transport |
| GO_0010881 | Biological process | regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion |
| GO_0045823 | Biological process | positive regulation of heart contraction |
| GO_0010880 | Biological process | regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum |
| GO_1901844 | Biological process | regulation of cell communication by electrical coupling involved in cardiac conduction |
| GO_0060314 | Biological process | regulation of ryanodine-sensitive calcium-release channel activity |
| GO_1901899 | Biological process | positive regulation of relaxation of cardiac muscle |
| GO_0010460 | Biological process | positive regulation of heart rate |
| GO_0030018 | Cellular component | Z disc |
| GO_0033018 | Cellular component | sarcoplasmic reticulum lumen |
| GO_0005788 | Cellular component | endoplasmic reticulum lumen |
| GO_0033017 | Cellular component | sarcoplasmic reticulum membrane |
| GO_0044325 | Molecular function | transmembrane transporter binding |
| GO_0051117 | Molecular function | ATPase binding |
| GO_0005509 | Molecular function | calcium ion binding |
| GO_0005515 | Molecular function | protein binding |
| Gene name | HRC |
| Protein name | Histidine rich calcium binding protein Alternative protein HRC Sarcoplasmic reticulum histidine-rich calcium-binding protein Histidine-rich calcium-binding protein |
| Synonyms | HCP |
| Description | FUNCTION: May play a role in the regulation of calcium sequestration or release in the SR of skeletal and cardiac muscle. |
| Accessions | ENST00000595625.1 M0QY84 M0QZ43 Q2M1I0 ENST00000598858.5 ENST00000252825.9 P23327 L8E9Z3 B5TMG5 |
