HOXB-AS3 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of HOXB-AS3 at tissue level.

III. Associated gene sets

GO_0043484Biological processregulation of RNA splicing
GO_2000632Biological processnegative regulation of pre-miRNA processing
GO_0008380Biological processRNA splicing
GO_0006397Biological processmRNA processing
GO_0050821Biological processprotein stabilization
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameHOXB-AS3
Protein nameHOXB-AS3 peptide
Synonyms
DescriptionFUNCTION: Blocks the binding of HNRNPA1 to the intronic sequences flanking exon 9 of the PKM gene by competitively binding to the HNRNPA1 RGG-box motif . This inhibits inclusion of exon 9 and promotes inclusion of exon 10, suppressing formation of the PKM M2 isoform and promoting production of the M1 isoform . Also suppresses HNRNPA1-mediated processing of microRNA 18a (miR-18a) . Promotes MYC stability through interaction with IGF2BP2 . .

AccessionsC0HLZ6