HMMR report

I. Expression across cell types

Insufficient scRNA-seq data for expression of HMMR at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of HMMR at tissue level.

III. Associated gene sets

GO_0030214Biological processhyaluronan catabolic process
GO_0006898Biological processreceptor-mediated endocytosis
GO_0005813Cellular componentcentrosome
GO_0009986Cellular componentcell surface
GO_0005829Cellular componentcytosol
GO_0015630Cellular componentmicrotubule cytoskeleton
GO_0005886Cellular componentplasma membrane
GO_0005819Cellular componentspindle
GO_0016020Cellular componentmembrane
GO_0038024Molecular functioncargo receptor activity
GO_0005515Molecular functionprotein binding
GO_0005540Molecular functionhyaluronic acid binding

IV. Literature review

[source]
Gene nameHMMR
Protein nameHyaluronan mediated motility receptor (Intracellular hyaluronic acid-binding protein) (Receptor for hyaluronan-mediated motility) (CD antigen CD168)
HMMR protein
Hyaluronan-mediated motility receptor
Hyaluronan mediated motility receptor
SynonymsRHAMM
IHABP
DescriptionFUNCTION: Receptor for hyaluronic acid (HA) (By similarity). Involved in cell motility (By similarity). When hyaluronan binds to HMMR, the phosphorylation of a number of proteins, including PTK2/FAK1 occurs. May also be involved in cellular transformation and metastasis formation, and in regulating extracellular-regulated kinase (ERK) activity. May act as a regulator of adipogenisis (By similarity). .

AccessionsE5RIH2
Q6NSC0
Q6PG44
ENST00000520345.5
ENST00000353866.7 [O75330-2]
ENST00000358715.3 [O75330-1]
ENST00000393915.9 [O75330-3]
Q05D84
ENST00000432118.6 [O75330-4]
E5RI30
Q6PIR6
Q05DM0
ENST00000522094.5
B9UCQ3
O75330