HK3 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of HK3 at tissue level.

III. Associated gene sets

GO_0006002Biological processfructose 6-phosphate metabolic process
GO_0046835Biological processcarbohydrate phosphorylation
GO_0061621Biological processcanonical glycolysis
GO_0051156Biological processglucose 6-phosphate metabolic process
GO_0001678Biological processintracellular glucose homeostasis
GO_0006096Biological processglycolytic process
GO_0006006Biological processglucose metabolic process
GO_0034774Cellular componentsecretory granule lumen
GO_1904813Cellular componentficolin-1-rich granule lumen
GO_0005739Cellular componentmitochondrion
GO_0005829Cellular componentcytosol
GO_0005576Cellular componentextracellular region
GO_0004396Molecular functionhexokinase activity
GO_0005536Molecular functionD-glucose binding
GO_0005515Molecular functionprotein binding
GO_0005524Molecular functionATP binding
GO_0008865Molecular functionfructokinase activity
GO_0004340Molecular functionglucokinase activity

IV. Literature review

[source]
Gene nameHK3
Protein nameHexokinase III (EC 2.7.1.1)
Hexokinase-3 (EC 2.7.1.1) (Hexokinase type III) (HK III) (Hexokinase-C)
Phosphotransferase (EC 2.7.1.-)
Hexokinase 3
Synonyms
DescriptionFUNCTION: Catalyzes the phosphorylation of hexose, such as D-glucose and D-fructose, to hexose 6-phosphate (D-glucose 6-phosphate and D-fructose 6-phosphate, respectively) . Mediates the initial step of glycolysis by catalyzing phosphorylation of D-glucose to D-glucose 6-phosphate . .

AccessionsENST00000504910.1
Q16779
ENST00000292432.10
H0Y9N6
P52790
ENST00000514058.1
ENST00000509717.5
H0YAG4
H0Y8U9