HIPK4 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of HIPK4 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of HIPK4 at tissue level.

III. Associated gene sets

GO_0018105Biological processpeptidyl-serine phosphorylation
GO_0018107Biological processpeptidyl-threonine phosphorylation
GO_1901796Biological processregulation of signal transduction by p53 class mediator
GO_0006338Biological processchromatin remodeling
GO_0005737Cellular componentcytoplasm
GO_0005634Cellular componentnucleus
GO_0004713Molecular functionprotein tyrosine kinase activity
GO_0004674Molecular functionprotein serine/threonine kinase activity
GO_0005515Molecular functionprotein binding
GO_0106310Molecular functionprotein serine kinase activity
GO_0035173Molecular functionhistone kinase activity
GO_0005524Molecular functionATP binding

IV. Literature review

[source]
Gene nameHIPK4
Protein nameHomeodomain interacting protein kinase 4, isoform CRA_b (Testicular tissue protein Li 87)
Homeodomain-interacting protein kinase 4 (EC 2.7.11.1)
SynonymshCG_20798
DescriptionFUNCTION: Protein kinase that phosphorylates human TP53 at Ser-9, and thus induces TP53 repression of BIRC5 promoter (By similarity). May act as a corepressor of transcription factors (Potential). .

AccessionsQ8NE63
ENST00000291823.3
A0A140VJL1