Name | Number of supported studies | Average coverage | |
---|---|---|---|
hepatocyte | 4 studies | 52% ± 19% |
Insufficient scRNA-seq data for expression of HGFAC at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
liver | 100% | 18166.46 | 226 / 226 | 80% | 70.91 | 323 / 406 |
brain | 92% | 187.68 | 2434 / 2642 | 78% | 3.03 | 553 / 705 |
ovary | 84% | 49.71 | 152 / 180 | 62% | 2.55 | 266 / 430 |
kidney | 98% | 113.92 | 87 / 89 | 30% | 3.47 | 267 / 901 |
uterus | 88% | 74.31 | 150 / 170 | 25% | 0.87 | 117 / 459 |
prostate | 98% | 107.33 | 241 / 245 | 9% | 0.22 | 46 / 502 |
bladder | 90% | 48.90 | 19 / 21 | 9% | 0.23 | 45 / 504 |
lung | 79% | 40.58 | 456 / 578 | 14% | 0.41 | 163 / 1155 |
esophagus | 70% | 50.43 | 1018 / 1445 | 6% | 0.12 | 11 / 183 |
breast | 59% | 34.97 | 271 / 459 | 12% | 0.28 | 138 / 1118 |
intestine | 67% | 38.64 | 644 / 966 | 3% | 0.26 | 16 / 527 |
thymus | 63% | 32.38 | 411 / 653 | 5% | 0.10 | 29 / 605 |
blood vessel | 58% | 24.01 | 779 / 1335 | 0% | 0 | 0 / 0 |
stomach | 52% | 30.51 | 187 / 359 | 2% | 0.02 | 5 / 286 |
muscle | 53% | 32.16 | 428 / 803 | 0% | 0 | 0 / 0 |
adipose | 29% | 11.60 | 350 / 1204 | 0% | 0 | 0 / 0 |
spleen | 27% | 18.49 | 66 / 241 | 0% | 0 | 0 / 0 |
heart | 26% | 10.05 | 228 / 861 | 0% | 0 | 0 / 0 |
pancreas | 21% | 7.28 | 69 / 328 | 4% | 0.06 | 7 / 178 |
skin | 14% | 4.86 | 249 / 1809 | 7% | 0.22 | 32 / 472 |
adrenal gland | 9% | 3.17 | 22 / 258 | 4% | 0.11 | 10 / 230 |
tonsil | 0% | 0 | 0 / 0 | 4% | 0.06 | 2 / 45 |
peripheral blood | 1% | 0.89 | 13 / 929 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 1% | 0.02 | 1 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0007596 | Biological process | blood coagulation |
GO_0006508 | Biological process | proteolysis |
GO_0031638 | Biological process | zymogen activation |
GO_0005615 | Cellular component | extracellular space |
GO_0005791 | Cellular component | rough endoplasmic reticulum |
GO_0005829 | Cellular component | cytosol |
GO_0005576 | Cellular component | extracellular region |
GO_0008236 | Molecular function | serine-type peptidase activity |
GO_0005515 | Molecular function | protein binding |
GO_0004252 | Molecular function | serine-type endopeptidase activity |
Gene name | HGFAC |
Protein name | Hepatocyte growth factor activator (HGF activator) (HGFA) (EC 3.4.21.-) [Cleaved into: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain] HGF activator |
Synonyms | |
Description | FUNCTION: Activates hepatocyte growth factor (HGF) by converting it from a single chain to a heterodimeric form. |
Accessions | D6RAR4 Q04756 ENST00000382774.8 ENST00000511533.1 |