HGFAC report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of HGFAC at tissue level.

III. Associated gene sets

GO_0007596Biological processblood coagulation
GO_0006508Biological processproteolysis
GO_0031638Biological processzymogen activation
GO_0005615Cellular componentextracellular space
GO_0005791Cellular componentrough endoplasmic reticulum
GO_0005829Cellular componentcytosol
GO_0005576Cellular componentextracellular region
GO_0008236Molecular functionserine-type peptidase activity
GO_0005515Molecular functionprotein binding
GO_0004252Molecular functionserine-type endopeptidase activity

IV. Literature review

[source]
Gene nameHGFAC
Protein nameHepatocyte growth factor activator (HGF activator) (HGFA) (EC 3.4.21.-) [Cleaved into: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain]
HGF activator
Synonyms
DescriptionFUNCTION: Activates hepatocyte growth factor (HGF) by converting it from a single chain to a heterodimeric form.

AccessionsD6RAR4
Q04756
ENST00000382774.8
ENST00000511533.1