Name | Number of supported studies | Average coverage | |
---|---|---|---|
microglial cell | 11 studies | 28% ± 10% | |
glutamatergic neuron | 10 studies | 39% ± 23% | |
astrocyte | 10 studies | 30% ± 14% | |
endothelial cell | 9 studies | 24% ± 13% | |
oligodendrocyte precursor cell | 9 studies | 27% ± 13% | |
GABAergic neuron | 8 studies | 42% ± 21% | |
interneuron | 6 studies | 44% ± 24% | |
macrophage | 6 studies | 39% ± 6% | |
endothelial cell of lymphatic vessel | 6 studies | 25% ± 6% | |
fibroblast | 6 studies | 23% ± 8% | |
neuron | 4 studies | 24% ± 7% | |
retina horizontal cell | 4 studies | 19% ± 4% | |
GABAergic interneuron | 3 studies | 30% ± 5% | |
granule cell | 3 studies | 23% ± 3% | |
myeloid cell | 3 studies | 20% ± 3% | |
smooth muscle cell | 3 studies | 22% ± 5% |
Name | Number of supported studies | Average coverage | |
---|---|---|---|
brain | 11 studies | 34% ± 20% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
prostate | 100% | 2615.58 | 245 / 245 | 98% | 5.07 | 493 / 502 |
breast | 100% | 1560.73 | 459 / 459 | 97% | 6.98 | 1090 / 1118 |
brain | 98% | 1215.99 | 2579 / 2642 | 100% | 5.96 | 703 / 705 |
thymus | 100% | 1569.11 | 653 / 653 | 96% | 4.06 | 578 / 605 |
lung | 100% | 1469.99 | 577 / 578 | 95% | 2.94 | 1098 / 1155 |
esophagus | 100% | 1675.51 | 1441 / 1445 | 95% | 3.75 | 174 / 183 |
adrenal gland | 100% | 1118.26 | 258 / 258 | 95% | 3.98 | 218 / 230 |
ovary | 100% | 2424.92 | 180 / 180 | 94% | 3.06 | 406 / 430 |
pancreas | 98% | 725.13 | 323 / 328 | 94% | 3.10 | 168 / 178 |
kidney | 100% | 980.94 | 89 / 89 | 92% | 3.97 | 827 / 901 |
uterus | 100% | 2549.66 | 170 / 170 | 91% | 3.53 | 417 / 459 |
bladder | 100% | 2047.29 | 21 / 21 | 81% | 2.50 | 408 / 504 |
skin | 100% | 990.11 | 1804 / 1809 | 81% | 3.09 | 380 / 472 |
stomach | 100% | 1051.19 | 358 / 359 | 65% | 1.82 | 186 / 286 |
intestine | 100% | 1460.90 | 962 / 966 | 52% | 1.16 | 273 / 527 |
liver | 62% | 242.83 | 140 / 226 | 58% | 1.38 | 235 / 406 |
blood vessel | 100% | 2585.29 | 1335 / 1335 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 100% | 1.64 | 1 / 1 |
adipose | 100% | 1503.83 | 1203 / 1204 | 0% | 0 | 0 / 0 |
spleen | 100% | 850.89 | 240 / 241 | 0% | 0 | 0 / 0 |
muscle | 98% | 768.00 | 789 / 803 | 0% | 0 | 0 / 0 |
heart | 88% | 682.94 | 760 / 861 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 87% | 2.20 | 39 / 45 |
eye | 0% | 0 | 0 / 0 | 55% | 1.42 | 44 / 80 |
lymph node | 0% | 0 | 0 / 0 | 45% | 0.85 | 13 / 29 |
peripheral blood | 5% | 21.44 | 49 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0000209 | Biological process | protein polyubiquitination |
GO_0005829 | Cellular component | cytosol |
GO_0061630 | Molecular function | ubiquitin protein ligase activity |
Gene name | HECTD2 |
Protein name | HECT domain E3 ubiquitin protein ligase 2 Probable E3 ubiquitin-protein ligase HECTD2 (EC 2.3.2.26) (HECT domain-containing protein 2) (HECT-type E3 ubiquitin transferase HECTD2) Alternative protein HECTD2 HECT-type E3 ubiquitin transferase (EC 2.3.2.26) |
Synonyms | |
Description | FUNCTION: E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. .; FUNCTION: (Microbial infection) Catalyzes ubiquitination of Botulinum neurotoxin A light chain (LC) of C.botulinum neurotoxin type A (BoNT/A). . |
Accessions | ENST00000446394.5 ENST00000298068.10 [Q5U5R9-1] E7ERR3 Q5U5R9 ENST00000371667.1 ENST00000631422.1 A0A0J9YVV1 ENST00000371681.8 [Q5U5R9-2] X6R824 L8ECN8 |