I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| epithelial cell | 4 studies | 29% ± 10% | |
| ciliated cell | 3 studies | 23% ± 4% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| epithelial cell | 4 studies | 29% ± 10% | |
| ciliated cell | 3 studies | 23% ± 4% |
Insufficient scRNA-seq data for expression of HDDC3 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| pancreas | 100% | 389.76 | 328 / 328 | 100% | 3.27 | 178 / 178 |
| brain | 100% | 333.94 | 2640 / 2642 | 100% | 3.55 | 703 / 705 |
| ovary | 100% | 217.90 | 180 / 180 | 100% | 3.90 | 428 / 430 |
| thymus | 100% | 330.64 | 653 / 653 | 99% | 3.88 | 601 / 605 |
| stomach | 100% | 263.51 | 358 / 359 | 99% | 3.66 | 284 / 286 |
| skin | 100% | 343.89 | 1809 / 1809 | 99% | 3.70 | 467 / 472 |
| kidney | 100% | 351.87 | 89 / 89 | 99% | 3.35 | 891 / 901 |
| prostate | 100% | 252.39 | 245 / 245 | 99% | 4.82 | 496 / 502 |
| bladder | 100% | 215.62 | 21 / 21 | 98% | 3.83 | 495 / 504 |
| intestine | 100% | 227.06 | 963 / 966 | 98% | 4.36 | 518 / 527 |
| uterus | 100% | 182.49 | 170 / 170 | 98% | 3.28 | 448 / 459 |
| liver | 100% | 260.22 | 226 / 226 | 97% | 3.27 | 395 / 406 |
| lung | 99% | 229.24 | 572 / 578 | 98% | 3.20 | 1132 / 1155 |
| breast | 100% | 376.91 | 459 / 459 | 97% | 3.51 | 1080 / 1118 |
| adrenal gland | 100% | 509.00 | 258 / 258 | 96% | 3.87 | 221 / 230 |
| esophagus | 99% | 167.01 | 1433 / 1445 | 93% | 2.16 | 170 / 183 |
| adipose | 100% | 338.72 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 4.78 | 29 / 29 |
| spleen | 100% | 420.60 | 241 / 241 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 100% | 3.24 | 1 / 1 |
| heart | 98% | 211.65 | 844 / 861 | 0% | 0 | 0 / 0 |
| muscle | 98% | 200.31 | 787 / 803 | 0% | 0 | 0 / 0 |
| peripheral blood | 98% | 266.77 | 910 / 929 | 0% | 0 | 0 / 0 |
| blood vessel | 98% | 142.00 | 1306 / 1335 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 98% | 3.46 | 78 / 80 |
| tonsil | 0% | 0 | 0 / 0 | 96% | 2.84 | 43 / 45 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0046872 | Molecular function | metal ion binding |
| GO_0008893 | Molecular function | guanosine-3',5'-bis(diphosphate) 3'-diphosphatase activity |
| GO_0005515 | Molecular function | protein binding |
| Gene name | HDDC3 |
| Protein name | Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase MESH1 (EC 3.1.7.2) (Metazoan SpoT homolog 1) (Penta-phosphate guanosine-3'-pyrophosphohydrolase) Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase MESH1 (EC 3.1.7.2) (HD domain-containing protein 3) (Metazoan SpoT homolog 1) (MESH1) (Penta-phosphate guanosine-3'-pyrophosphohydrolase) ((ppGpp)ase) |
| Synonyms | MESH1 |
| Description | FUNCTION: ppGpp hydrolyzing enzyme involved in starvation response. . FUNCTION: ppGpp hydrolyzing enzyme involved in starvation response. . FUNCTION: ppGpp hydrolyzing enzyme involved in starvation response. . |
| Accessions | Q8N4P3 ENST00000646620.1 [Q8N4P3-1] ENST00000559898.5 ENST00000561036.1 H0YKT9 ENST00000394272.8 [Q8N4P3-1] ENST00000330334.7 [Q8N4P3-2] H0YNP9 |
