I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| oligodendrocyte | 7 studies | 24% ± 8% | |
| epithelial cell | 3 studies | 18% ± 0% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| oligodendrocyte | 7 studies | 24% ± 8% | |
| epithelial cell | 3 studies | 18% ± 0% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 3 studies | 26% ± 4% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 100% | 5735.35 | 2642 / 2642 | 100% | 40.37 | 702 / 705 |
| thymus | 100% | 2196.63 | 651 / 653 | 100% | 24.67 | 602 / 605 |
| prostate | 100% | 2039.46 | 244 / 245 | 99% | 21.86 | 499 / 502 |
| pancreas | 100% | 2444.65 | 328 / 328 | 99% | 20.48 | 176 / 178 |
| uterus | 99% | 1767.48 | 169 / 170 | 98% | 17.41 | 448 / 459 |
| kidney | 99% | 2218.00 | 88 / 89 | 98% | 21.41 | 880 / 901 |
| ovary | 100% | 1873.49 | 180 / 180 | 96% | 13.62 | 414 / 430 |
| intestine | 99% | 1856.30 | 957 / 966 | 96% | 17.75 | 504 / 527 |
| bladder | 100% | 1775.76 | 21 / 21 | 94% | 16.12 | 473 / 504 |
| skin | 97% | 1468.72 | 1757 / 1809 | 96% | 16.61 | 455 / 472 |
| breast | 94% | 1172.35 | 432 / 459 | 98% | 34.25 | 1094 / 1118 |
| stomach | 97% | 1236.52 | 348 / 359 | 89% | 15.35 | 255 / 286 |
| esophagus | 100% | 2085.33 | 1444 / 1445 | 86% | 8.94 | 157 / 183 |
| adrenal gland | 95% | 1123.86 | 245 / 258 | 90% | 25.16 | 206 / 230 |
| lung | 89% | 1064.43 | 514 / 578 | 90% | 12.10 | 1044 / 1155 |
| liver | 19% | 156.19 | 42 / 226 | 87% | 13.11 | 353 / 406 |
| eye | 0% | 0 | 0 / 0 | 100% | 37.37 | 80 / 80 |
| ureter | 0% | 0 | 0 / 0 | 100% | 14.39 | 1 / 1 |
| blood vessel | 99% | 1707.30 | 1319 / 1335 | 0% | 0 | 0 / 0 |
| muscle | 98% | 1796.18 | 786 / 803 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 98% | 17.02 | 44 / 45 |
| heart | 97% | 2301.27 | 833 / 861 | 0% | 0 | 0 / 0 |
| adipose | 85% | 867.82 | 1018 / 1204 | 0% | 0 | 0 / 0 |
| spleen | 57% | 451.04 | 137 / 241 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 28% | 1.84 | 8 / 29 |
| peripheral blood | 2% | 9.91 | 15 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0006325 | Biological process | chromatin organization |
| GO_0014003 | Biological process | oligodendrocyte development |
| GO_0040029 | Biological process | epigenetic regulation of gene expression |
| GO_0000118 | Cellular component | histone deacetylase complex |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0005634 | Cellular component | nucleus |
| GO_0004407 | Molecular function | histone deacetylase activity |
| GO_0140297 | Molecular function | DNA-binding transcription factor binding |
| GO_0005515 | Molecular function | protein binding |
| Gene name | HDAC11 |
| Protein name | Histone deacetylase 11 (HD11) (EC 3.5.1.98) Histone deacetylase 11 HDAC11 protein |
| Synonyms | DKFZp434L0312 hCG_28391 |
| Description | FUNCTION: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. . |
| Accessions | ENST00000402259.5 Q658J9 E7ETT9 ENST00000446613.6 Q96DB2 B5MCU6 B5MCS3 ENST00000416248.5 C9JBI4 C9JMH0 ENST00000404548.5 ENST00000434848.5 ENST00000405478.5 C9J528 B5MCV5 ENST00000295757.8 [Q96DB2-1] B5MCQ6 ENST00000404040.5 B5MD06 F8WF94 ENST00000433119.5 ENST00000437379.2 B5MC52 ENST00000405025.5 ENST00000455904.5 ENST00000522202.5 [Q96DB2-2] ENST00000402271.5 C9JEC8 Q6IA14 ENST00000425430.5 ENST00000418189.5 |
