Insufficient scRNA-seq data for expression of HCN3 at single-cell level.
Insufficient scRNA-seq data for expression of HCN3 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
intestine | 100% | 1080.56 | 964 / 966 | 94% | 6.35 | 494 / 527 |
brain | 96% | 1511.84 | 2545 / 2642 | 97% | 9.56 | 683 / 705 |
esophagus | 98% | 684.91 | 1419 / 1445 | 95% | 6.42 | 173 / 183 |
adrenal gland | 99% | 744.86 | 256 / 258 | 92% | 9.36 | 212 / 230 |
stomach | 98% | 477.67 | 353 / 359 | 90% | 6.04 | 258 / 286 |
uterus | 100% | 837.90 | 170 / 170 | 88% | 6.54 | 405 / 459 |
bladder | 100% | 642.90 | 21 / 21 | 88% | 5.87 | 442 / 504 |
kidney | 100% | 1336.42 | 89 / 89 | 85% | 5.25 | 765 / 901 |
pancreas | 94% | 381.13 | 309 / 328 | 89% | 5.68 | 158 / 178 |
breast | 97% | 496.30 | 443 / 459 | 84% | 4.46 | 935 / 1118 |
skin | 95% | 1061.77 | 1719 / 1809 | 84% | 4.90 | 398 / 472 |
ovary | 99% | 832.26 | 179 / 180 | 77% | 3.91 | 332 / 430 |
liver | 98% | 1731.98 | 221 / 226 | 77% | 4.73 | 314 / 406 |
lung | 93% | 356.36 | 537 / 578 | 78% | 4.33 | 896 / 1155 |
prostate | 100% | 807.81 | 244 / 245 | 60% | 2.01 | 301 / 502 |
thymus | 100% | 907.60 | 653 / 653 | 58% | 1.96 | 349 / 605 |
spleen | 98% | 363.19 | 236 / 241 | 0% | 0 | 0 / 0 |
blood vessel | 89% | 312.25 | 1194 / 1335 | 0% | 0 | 0 / 0 |
adipose | 88% | 383.73 | 1056 / 1204 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 80% | 4.63 | 36 / 45 |
heart | 54% | 138.26 | 468 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 39% | 1.12 | 31 / 80 |
lymph node | 0% | 0 | 0 / 0 | 38% | 1.24 | 11 / 29 |
peripheral blood | 22% | 97.65 | 207 / 929 | 0% | 0 | 0 / 0 |
muscle | 17% | 37.23 | 135 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_1903351 | Biological process | cellular response to dopamine |
GO_0071320 | Biological process | cellular response to cAMP |
GO_0035725 | Biological process | sodium ion transmembrane transport |
GO_0042391 | Biological process | regulation of membrane potential |
GO_0071805 | Biological process | potassium ion transmembrane transport |
GO_0003254 | Biological process | regulation of membrane depolarization |
GO_0030424 | Cellular component | axon |
GO_0098855 | Cellular component | HCN channel complex |
GO_0043025 | Cellular component | neuronal cell body |
GO_0005886 | Cellular component | plasma membrane |
GO_0044316 | Cellular component | cone cell pedicle |
GO_0030425 | Cellular component | dendrite |
GO_0005248 | Molecular function | voltage-gated sodium channel activity |
GO_0030552 | Molecular function | cAMP binding |
GO_0005249 | Molecular function | voltage-gated potassium channel activity |
GO_0005515 | Molecular function | protein binding |
Gene name | HCN3 |
Protein name | Hyperpolarization activated cyclic nucleotide-gated potassium channel Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3 HCN3 protein |
Synonyms | KIAA1535 |
Description | FUNCTION: Hyperpolarization-activated potassium channel. May also facilitate the permeation of sodium ions. . |
Accessions | ENST00000368358.4 Q86WJ5 Q2T9L6 Q9P1Z3 ENST00000575670.1 |