HAS1 | OmnibusX

Name	Number of supported studies	Average coverage
mesothelial cell	6 studies	44% ± 9%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of HAS1 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
ovary	100%	1842.90	180 / 180	22%	1.13	95 / 430
brain	81%	175.95	2127 / 2642	30%	0.99	208 / 705
skin	91%	567.51	1650 / 1809	17%	1.38	82 / 472
lung	54%	351.59	311 / 578	27%	1.28	311 / 1155
intestine	50%	187.70	485 / 966	22%	2.61	117 / 527
bladder	43%	331.33	9 / 21	28%	2.28	141 / 504
adipose	70%	2156.51	840 / 1204	0%	0	0 / 0
esophagus	36%	133.56	527 / 1445	30%	1.26	54 / 183
stomach	33%	131.22	118 / 359	29%	1.21	82 / 286
pancreas	5%	6.72	17 / 328	56%	6.24	100 / 178
breast	30%	102.21	137 / 459	30%	1.42	338 / 1118
heart	56%	377.14	483 / 861	0%	0	0 / 0
uterus	25%	63.56	42 / 170	20%	2.63	94 / 459
blood vessel	44%	241.94	587 / 1335	0%	0	0 / 0
thymus	27%	63.06	177 / 653	14%	1.28	85 / 605
peripheral blood	23%	37.60	211 / 929	0%	0	0 / 0
lymph node	0%	0	0 / 0	21%	1.13	6 / 29
adrenal gland	7%	7.26	18 / 258	12%	4.68	27 / 230
liver	3%	3.95	6 / 226	14%	0.60	57 / 406
spleen	11%	13.04	27 / 241	0%	0	0 / 0
prostate	7%	19.06	17 / 245	2%	0.07	10 / 502
tonsil	0%	0	0 / 0	9%	0.13	4 / 45
kidney	2%	3.67	2 / 89	5%	0.19	49 / 901
muscle	3%	6.37	27 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
eye	0%	0	0 / 0	0%	0	0 / 80
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0030213	Biological process	hyaluronan biosynthetic process
GO_0007155	Biological process	cell adhesion
GO_0045226	Biological process	extracellular polysaccharide biosynthetic process
GO_0010764	Biological process	negative regulation of fibroblast migration
GO_0085029	Biological process	extracellular matrix assembly
GO_0036120	Biological process	cellular response to platelet-derived growth factor stimulus
GO_0006024	Biological process	glycosaminoglycan biosynthetic process
GO_0005794	Cellular component	Golgi apparatus
GO_0005886	Cellular component	plasma membrane
GO_0050501	Molecular function	hyaluronan synthase activity
GO_0042802	Molecular function	identical protein binding
GO_0005515	Molecular function	protein binding

Gene name	HAS1
Protein name	hyaluronan synthase (EC 2.4.1.212) Hyaluronan synthase 1 Hyaluronan synthase 1 (EC 2.4.1.212) (Hyaluronate synthase 1) (Hyaluronic acid synthase 1) (HA synthase 1) (HuHAS1)
Synonyms	hCG_91965 HAS
Description	FUNCTION: Catalyzes the addition of GlcNAc or GlcUA monosaccharides to the nascent hyaluronan polymer. Therefore, it is essential to hyaluronan synthesis a major component of most extracellular matrices that has a structural role in tissues architectures and regulates cell adhesion, migration and differentiation. This is one of the isozymes catalyzing that reaction. Also able to catalyze the synthesis of chito-oligosaccharide depending on the substrate (By similarity). .
Accessions	G3V1S7 M0R2V0 ENST00000601667.5 M0QXH4 ENST00000601714.5 D2N2G5 M0R1L3 ENST00000594621.1 ENST00000540069.7 Q8IYH3 ENST00000222115.5 Q92839

HAS1 report