HAO2 | OmnibusX

Name	Number of supported studies	Average coverage
epithelial cell of proximal tubule	6 studies	29% ± 8%	Explore
hepatocyte	4 studies	37% ± 19%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of HAO2 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
liver	100%	8211.82	226 / 226	74%	65.29	302 / 406
kidney	100%	4146.67	89 / 89	72%	35.67	649 / 901
adrenal gland	100%	64.33	257 / 258	7%	0.36	15 / 230
spleen	76%	20.20	184 / 241	0%	0	0 / 0
breast	66%	8.34	305 / 459	4%	2.31	40 / 1118
skin	64%	158.93	1153 / 1809	5%	0.83	24 / 472
prostate	64%	7.54	157 / 245	0%	0.06	1 / 502
ovary	64%	5.09	115 / 180	0%	0	0 / 430
adipose	62%	7.18	743 / 1204	0%	0	0 / 0
thymus	46%	3.40	303 / 653	4%	0.54	24 / 605
intestine	42%	4.45	407 / 966	1%	0.19	3 / 527
uterus	38%	2.86	65 / 170	2%	0.10	7 / 459
bladder	38%	3.76	8 / 21	1%	0.07	4 / 504
lung	35%	2.42	203 / 578	0%	0.00	1 / 1155
blood vessel	34%	2.68	450 / 1335	0%	0	0 / 0
peripheral blood	28%	16.22	264 / 929	0%	0	0 / 0
pancreas	26%	2.09	85 / 328	2%	0.12	3 / 178
stomach	25%	1.64	90 / 359	2%	0.11	5 / 286
esophagus	23%	1.59	333 / 1445	2%	0.11	4 / 183
brain	21%	1.26	548 / 2642	0%	0.00	1 / 705
heart	20%	1.48	176 / 861	0%	0	0 / 0
lymph node	0%	0	0 / 0	10%	12.55	3 / 29
muscle	8%	0.43	68 / 803	0%	0	0 / 0
tonsil	0%	0	0 / 0	4%	0.25	2 / 45
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
eye	0%	0	0 / 0	0%	0	0 / 80
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0019395	Biological process	fatty acid oxidation
GO_0001561	Biological process	fatty acid alpha-oxidation
GO_0005829	Cellular component	cytosol
GO_0005782	Cellular component	peroxisomal matrix
GO_0010181	Molecular function	FMN binding
GO_0003973	Molecular function	(S)-2-hydroxy-acid oxidase activity
GO_0005515	Molecular function	protein binding

Gene name	HAO2
Protein name	2-Hydroxyacid oxidase 2 (HAOX2) (EC 1.1.3.15) ((S)-2-hydroxy-acid oxidase, peroxisomal) (Cell growth-inhibiting gene 16 protein) (Long chain alpha-hydroxy acid oxidase) (Long-chain L-2-hydroxy acid oxidase) Hydroxyacid oxidase 2
Synonyms	HAOX2 GIG16
Description	FUNCTION: Oxidase that catalyzes the oxidation of medium and long chain hydroxyacids such as 2-hydroxyhexadecanoate and 2-hydroxyoctanoate, to the correspondong 2-oxoacids . Its role in the oxidation of 2-hydroxy fatty acids may contribute to the general pathway of fatty acid alpha-oxidation (Probable). Active in vitro with the artificial electron acceptor 2,6-dichlorophenolindophenol (DCIP), but O2 is believed to be the physiological electron acceptor, leading to the production of H2O2. Is not active on glycolate, glyoxylate, L-lactate and 2-hydroxybutanoate . .
Accessions	ENST00000325945.4 [Q9NYQ3-1] Q9NYQ3 ENST00000361035.8 [Q9NYQ3-2] Q5QP02 ENST00000457318.5 ENST00000622548.4 [Q9NYQ3-1]

HAO2 report