H3Y2 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of H3Y2 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of H3Y2 at tissue level.

III. Associated gene sets

GO_0005654Cellular componentnucleoplasm
GO_0000786Cellular componentnucleosome
GO_0005634Cellular componentnucleus
GO_0046982Molecular functionprotein heterodimerization activity
GO_0003677Molecular functionDNA binding
GO_0030527Molecular functionstructural constituent of chromatin

IV. Literature review

[source]
Gene nameH3Y2
Protein nameHistone H3.X (Histone H3.Y2)
Synonyms
DescriptionFUNCTION: Primate-specific variant histone H3, which constitutes a core component of nucleosomes . Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling (Probable). .

AccessionsP0DPK5
ENST00000600799.3