H2BW2 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of H2BW2 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of H2BW2 at tissue level.

III. Associated gene sets

GO_0000786Cellular componentnucleosome
GO_0005634Cellular componentnucleus
GO_0046982Molecular functionprotein heterodimerization activity
GO_0003677Molecular functionDNA binding
GO_0030527Molecular functionstructural constituent of chromatin

IV. Literature review

[source]
Gene nameH2BW2
Protein nameH2B histone family, member M (H2B.W histone 2)
Histone H2B type F-M (Histone H2B.s) (H2B/s)
H2B histone family, member M
SynonymsLL0XNC01-240C2.2-001
H2BFM
LL0XNC01-240C2.2-002
DescriptionFUNCTION: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

AccessionsA9UJN3
ENST00000675318.3 [P0C1H6-2]
ENST00000355016.8 [P0C1H6-2]
P0C1H6
W0TYI6
ENST00000417637.1