H2BN1 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of H2BN1 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of H2BN1 at tissue level.

III. Associated gene sets

GO_0000786Cellular componentnucleosome
GO_0005634Cellular componentnucleus
GO_0046982Molecular functionprotein heterodimerization activity
GO_0003677Molecular functionDNA binding
GO_0030527Molecular functionstructural constituent of chromatin

IV. Literature review

[source]
Gene nameH2BN1
Protein nameHistone H2A.N (H2B.N) (H2B.N variant histone 1)
Synonyms
DescriptionFUNCTION: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. .

AccessionsENST00000704639.1
P0DW85