H2BC18 | OmnibusX

Name	Number of supported studies	Average coverage
microglial cell	3 studies	23% ± 4%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of H2BC18 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
prostate	96%	1937.49	234 / 245	93%	6.76	466 / 502
ovary	84%	1772.22	152 / 180	85%	3.26	366 / 430
lung	80%	1592.15	464 / 578	63%	2.76	731 / 1155
esophagus	42%	214.21	600 / 1445	80%	3.28	146 / 183
bladder	62%	333.81	13 / 21	58%	3.61	292 / 504
breast	42%	343.26	195 / 459	67%	4.00	752 / 1118
stomach	55%	312.36	196 / 359	50%	2.14	143 / 286
uterus	41%	506.41	69 / 170	56%	2.30	259 / 459
kidney	74%	494.60	66 / 89	23%	0.74	204 / 901
thymus	61%	343.92	401 / 653	32%	0.68	191 / 605
pancreas	25%	95.40	83 / 328	61%	2.85	109 / 178
peripheral blood	84%	3563.52	778 / 929	0%	0	0 / 0
adrenal gland	52%	115.12	134 / 258	28%	0.60	64 / 230
skin	54%	459.98	980 / 1809	24%	0.51	112 / 472
spleen	77%	805.52	186 / 241	0%	0	0 / 0
intestine	40%	261.20	386 / 966	36%	1.49	191 / 527
brain	43%	127.88	1139 / 2642	32%	0.71	226 / 705
liver	44%	228.88	100 / 226	19%	0.64	78 / 406
heart	38%	174.01	326 / 861	0%	0	0 / 0
blood vessel	29%	162.34	386 / 1335	0%	0	0 / 0
adipose	28%	270.12	342 / 1204	0%	0	0 / 0
lymph node	0%	0	0 / 0	24%	0.40	7 / 29
tonsil	0%	0	0 / 0	18%	0.33	8 / 45
eye	0%	0	0 / 0	11%	0.20	9 / 80
muscle	4%	10.59	29 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0070062	Cellular component	extracellular exosome
GO_0005654	Cellular component	nucleoplasm
GO_0005829	Cellular component	cytosol
GO_0000786	Cellular component	nucleosome
GO_0005634	Cellular component	nucleus
GO_0046982	Molecular function	protein heterodimerization activity
GO_0003677	Molecular function	DNA binding
GO_0030527	Molecular function	structural constituent of chromatin
GO_0003674	Molecular function	molecular_function

Gene name	H2BC18
Protein name	Histone H2B type 2-F (H2B-clustered histone 18)
Synonyms	HIST2H2BF
Description	FUNCTION: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Accessions	ENST00000369167.3 [Q5QNW6-1] ENST00000545683.1 [Q5QNW6-2] Q5QNW6

H2BC18 report