H2BC14 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of H2BC14 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of H2BC14 at tissue level.

III. Associated gene sets

GO_0006334Biological processnucleosome assembly
GO_0070062Cellular componentextracellular exosome
GO_0005654Cellular componentnucleoplasm
GO_0005829Cellular componentcytosol
GO_0000786Cellular componentnucleosome
GO_0005634Cellular componentnucleus
GO_0030527Molecular functionstructural constituent of chromatin
GO_0046982Molecular functionprotein heterodimerization activity
GO_0003677Molecular functionDNA binding

IV. Literature review

[source]
Gene nameH2BC14
Protein nameHistone H2B type 1-M (Histone H2B.e) (H2B/e)
SynonymsH2BFE
HIST1H2BM
DescriptionFUNCTION: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

AccessionsQ99879
ENST00000621112.2