I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| erythrocyte | 10 studies | 53% ± 19% | |
| erythroblast | 4 studies | 47% ± 20% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| erythrocyte | 10 studies | 53% ± 19% | |
| erythroblast | 4 studies | 47% ± 20% |
Insufficient scRNA-seq data for expression of GYPA at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| kidney | 93% | 57.07 | 83 / 89 | 4% | 0.08 | 34 / 901 |
| spleen | 88% | 139.73 | 212 / 241 | 0% | 0 | 0 / 0 |
| peripheral blood | 81% | 310.31 | 751 / 929 | 0% | 0 | 0 / 0 |
| brain | 71% | 7.90 | 1876 / 2642 | 0% | 0 | 0 / 705 |
| liver | 58% | 15.43 | 131 / 226 | 0% | 0.01 | 1 / 406 |
| lung | 56% | 23.01 | 326 / 578 | 0% | 0.00 | 1 / 1155 |
| thymus | 27% | 3.03 | 176 / 653 | 0% | 0 | 0 / 605 |
| adipose | 25% | 4.26 | 306 / 1204 | 0% | 0 | 0 / 0 |
| heart | 23% | 2.17 | 196 / 861 | 0% | 0 | 0 / 0 |
| breast | 21% | 2.17 | 98 / 459 | 0% | 0.00 | 2 / 1118 |
| blood vessel | 21% | 1.48 | 277 / 1335 | 0% | 0 | 0 / 0 |
| prostate | 17% | 1.00 | 42 / 245 | 0% | 0 | 0 / 502 |
| bladder | 14% | 0.62 | 3 / 21 | 0% | 0 | 0 / 504 |
| uterus | 14% | 0.94 | 23 / 170 | 0% | 0.00 | 1 / 459 |
| adrenal gland | 10% | 0.78 | 26 / 258 | 1% | 0.05 | 3 / 230 |
| ovary | 11% | 1.02 | 20 / 180 | 0% | 0.02 | 1 / 430 |
| esophagus | 10% | 0.75 | 143 / 1445 | 0% | 0 | 0 / 183 |
| muscle | 10% | 0.80 | 79 / 803 | 0% | 0 | 0 / 0 |
| intestine | 7% | 0.43 | 68 / 966 | 0% | 0.00 | 1 / 527 |
| stomach | 5% | 0.25 | 17 / 359 | 0% | 0 | 0 / 286 |
| skin | 4% | 0.20 | 71 / 1809 | 0% | 0 | 0 / 472 |
| pancreas | 3% | 0.23 | 11 / 328 | 0% | 0 | 0 / 178 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 45 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0046718 | Biological process | symbiont entry into host cell |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0005829 | Cellular component | cytosol |
| GO_0170014 | Cellular component | ankyrin-1 complex |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0016020 | Cellular component | membrane |
| GO_0042802 | Molecular function | identical protein binding |
| GO_0005515 | Molecular function | protein binding |
| GO_0001618 | Molecular function | virus receptor activity |
| Gene name | GYPA |
| Protein name | Glycophorin GPA Glycophorin B/glycophorin A fusion protein Glycophorin-A (MN sialoglycoprotein) (PAS-2) (Sialoglycoprotein alpha) (CD antigen CD235a) Glycophorin A (MNS blood group) (Glycophorin Erik I-IV) (HCG2026259, isoform CRA_g) Miltenberger V-like glycophorin Glycophorin A Glycophorin A Ria variant Glycophorin A (MNS blood group) |
| Synonyms | hCG_2026259 GPA GYPB fusion GPErik |
| Description | FUNCTION: Component of the ankyrin-1 complex, a multiprotein complex involved in the stability and shape of the erythrocyte membrane . Glycophorin A is the major intrinsic membrane protein of the erythrocyte. The N-terminal glycosylated segment, which lies outside the erythrocyte membrane, has MN blood group receptors. Appears to be important for the function of SLC4A1 and is required for high activity of SLC4A1. May be involved in translocation of SLC4A1 to the plasma membrane. .; FUNCTION: (Microbial infection) Appears to be a receptor for Hepatitis A virus (HAV). .; FUNCTION: (Microbial infection) Receptor for P.falciparum erythrocyte-binding antigen 175 (EBA-175); binding of EBA-175 is dependent on sialic acid residues of the O-linked glycans. . |
| Accessions | Q58HE5 A0A346RDY7 A0A2S1CSI3 ENST00000642295.1 Q13030 Q6WBG7 ENST00000360771.8 A0A346RE02 Q8WWP1 ENST00000535709.6 A0A5A4U9W7 A0A346RF80 G8CW02 Q16308 ENST00000512064.5 Q14418 A0A346RE18 Q58HE7 X5M4Z9 E7EQF3 A0A346RDZ9 K9JI14 A0A7G1PFV2 Q12831 A0A8E8D7U9 ENST00000504786.5 ENST00000324022.14 [P02724-3] A0A346RE16 P02724 Q14438 Q8WTS2 Q9UM93 ENST00000512789.5 ENST00000642738.1 A0A087WU29 ENST00000508337.1 Q8WWP2 A0A0P0BZ51 A0A0C4DFT7 A0A223IA57 E9PH25 ENST00000641688.3 K9JIK7 A0A346RE34 Q8WWP4 A0A8E8D9B7 ENST00000646447.1 [P02724-2] A0A5A4U638 ENST00000642713.1 [P02724-2] B8Q183 A0A346RDD8 ENST00000616983.4 E9PD10 A0A346RDZ3 A0A346RDZ4 A0A346RE19 A0A2R8Y7F9 D6RJD8 Q8WWP3 A0A0A1EPM9 ENST00000503627.2 ENST00000643148.1 Q14460 |
