GUCY2F | OmnibusX

Name	Number of supported studies	Average coverage
retinal rod cell	3 studies	24% ± 6%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of GUCY2F at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
lung	64%	4.90	368 / 578	0%	0.00	2 / 1155
spleen	59%	2.70	141 / 241	0%	0	0 / 0
uterus	50%	7.31	85 / 170	0%	0	0 / 459
bladder	48%	1.24	10 / 21	0%	0	0 / 504
blood vessel	40%	2.31	536 / 1335	0%	0	0 / 0
ovary	35%	1.27	63 / 180	0%	0	0 / 430
peripheral blood	34%	1.37	312 / 929	0%	0	0 / 0
brain	32%	1.33	852 / 2642	0%	0.00	1 / 705
intestine	26%	0.86	249 / 966	0%	0.00	1 / 527
kidney	24%	0.75	21 / 89	0%	0.01	1 / 901
esophagus	21%	0.68	303 / 1445	1%	0.01	1 / 183
prostate	20%	0.57	48 / 245	0%	0	0 / 502
stomach	17%	0.46	61 / 359	1%	0.01	2 / 286
adipose	17%	0.53	199 / 1204	0%	0	0 / 0
skin	16%	0.56	294 / 1809	0%	0	0 / 472
adrenal gland	16%	0.50	41 / 258	0%	0	0 / 230
breast	13%	0.41	59 / 459	0%	0.00	1 / 1118
thymus	8%	0.23	54 / 653	4%	0.23	27 / 605
muscle	10%	0.39	83 / 803	0%	0	0 / 0
heart	10%	0.26	84 / 861	0%	0	0 / 0
pancreas	9%	0.28	29 / 328	0%	0	0 / 178
liver	4%	0.13	10 / 226	0%	0	0 / 406
eye	0%	0	0 / 0	1%	0.11	1 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
tonsil	0%	0	0 / 0	0%	0	0 / 45
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0019934	Biological process	cGMP-mediated signaling
GO_0007601	Biological process	visual perception
GO_0006182	Biological process	cGMP biosynthetic process
GO_0007168	Biological process	receptor guanylyl cyclase signaling pathway
GO_0050908	Biological process	detection of light stimulus involved in visual perception
GO_0022400	Biological process	regulation of opsin-mediated signaling pathway
GO_0005886	Cellular component	plasma membrane
GO_0005640	Cellular component	nuclear outer membrane
GO_0097381	Cellular component	photoreceptor disc membrane
GO_0120200	Cellular component	rod photoreceptor outer segment
GO_0004016	Molecular function	adenylate cyclase activity
GO_0038023	Molecular function	signaling receptor activity
GO_0044877	Molecular function	protein-containing complex binding
GO_0001653	Molecular function	peptide receptor activity
GO_0042802	Molecular function	identical protein binding
GO_0004672	Molecular function	protein kinase activity
GO_0005525	Molecular function	GTP binding
GO_0005524	Molecular function	ATP binding
GO_0004383	Molecular function	guanylate cyclase activity

Gene name	GUCY2F
Protein name	Retinal guanylyl cyclase 2 (RETGC-2) (EC 4.6.1.2) (Guanylate cyclase 2F, retinal) (Guanylate cyclase F) (GC-F) (Rod outer segment membrane guanylate cyclase 2) (ROS-GC2)
Synonyms	RETGC2 GUC2F
Description	FUNCTION: Responsible for the synthesis of cyclic GMP (cGMP) in rods and cones of photoreceptors . Plays an essential role in phototransduction, by mediating cGMP replenishment (By similarity). May also participate in the trafficking of membrane-asociated proteins to the photoreceptor outer segment membrane (By similarity). .
Accessions	P51841 ENST00000218006.3

GUCY2F report