GUCA2B | OmnibusX

Name	Number of supported studies	Average coverage
enterocyte	7 studies	39% ± 20%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of GUCA2B at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
liver	75%	57.87	170 / 226	59%	14.85	238 / 406
intestine	63%	1205.38	604 / 966	35%	6.79	187 / 527
stomach	70%	246.38	251 / 359	26%	5.13	74 / 286
kidney	0%	0	0 / 89	35%	6.38	315 / 901
pancreas	7%	1.98	24 / 328	26%	1.90	46 / 178
bladder	0%	0	0 / 21	16%	2.47	82 / 504
esophagus	1%	0.75	9 / 1445	9%	0.66	17 / 183
lung	1%	0.21	5 / 578	6%	1.74	69 / 1155
ovary	0%	0	0 / 180	5%	0.34	20 / 430
uterus	0%	0	0 / 170	4%	0.82	18 / 459
breast	1%	2.50	5 / 459	0%	0.00	1 / 1118
skin	1%	0.27	20 / 1809	0%	0	0 / 472
prostate	1%	0.22	2 / 245	0%	0	0 / 502
adrenal gland	0%	0	0 / 258	0%	0.28	1 / 230
peripheral blood	0%	0.09	4 / 929	0%	0	0 / 0
adipose	0%	0.42	4 / 1204	0%	0	0 / 0
thymus	0%	0.04	1 / 653	0%	0	0 / 605
brain	0%	0.01	1 / 2642	0%	0	0 / 705
abdomen	0%	0	0 / 0	0%	0	0 / 0
blood vessel	0%	0	0 / 1335	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
eye	0%	0	0 / 0	0%	0	0 / 80
gingiva	0%	0	0 / 0	0%	0	0 / 0
heart	0%	0	0 / 861	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
muscle	0%	0	0 / 803	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
spleen	0%	0	0 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	0%	0	0 / 45
ureter	0%	0	0 / 0	0%	0	0 / 1

Gene name	GUCA2B
Protein name	Guanylate cyclase activator 2B [Cleaved into: Guanylate cyclase C-activating peptide 2 (Guanylate cyclase C-activating peptide II) (GCAP-II); Uroguanylin (UGN)]
Synonyms
Description	FUNCTION: Endogenous activator of intestinal guanylate cyclase. It stimulates this enzyme through the same receptor binding region as the heat-stable enterotoxins. May be a potent physiological regulator of intestinal fluid and electrolyte transport. May be an autocrine/paracrine regulator of intestinal salt and water transport.
Accessions	ENST00000372581.2 Q16661

GO_0019934	Biological process	cGMP-mediated signaling
GO_0070062	Cellular component	extracellular exosome
GO_0005576	Cellular component	extracellular region
GO_0030250	Molecular function	guanylate cyclase activator activity
GO_0005515	Molecular function	protein binding

GUCA2B report