GTF2E1 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of GTF2E1 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of GTF2E1 at tissue level.

III. Associated gene sets

GO_0006366Biological processtranscription by RNA polymerase II
GO_0006367Biological processtranscription initiation at RNA polymerase II promoter
GO_0001113Biological processtranscription open complex formation at RNA polymerase II promoter
GO_0005673Cellular componenttranscription factor TFIIE complex
GO_0005669Cellular componenttranscription factor TFIID complex
GO_0005654Cellular componentnucleoplasm
GO_0005829Cellular componentcytosol
GO_0005634Cellular componentnucleus
GO_0016251Molecular functionRNA polymerase II general transcription initiation factor activity
GO_0005515Molecular functionprotein binding
GO_0046872Molecular functionmetal ion binding

IV. Literature review

[source]
Gene nameGTF2E1
Protein nameGTF2E1 protein
General transcription factor IIE subunit 1 (General transcription factor IIE 56 kDa subunit) (Transcription initiation factor IIE subunit alpha) (TFIIE-alpha)
General transcription factor IIE subunit 1
SynonymsTF2E1
DescriptionFUNCTION: Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.

AccessionsC9IYL4
E9PER7
ENST00000484715.1
ENST00000469772.5
ENST00000283875.6
C9J329
P29083
ENST00000492959.1
Q05DN6