Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| endothelial cell | 18 studies | 28% ± 14% | |
| oligodendrocyte | 16 studies | 48% ± 16% | |
| astrocyte | 14 studies | 34% ± 16% | |
| glutamatergic neuron | 13 studies | 51% ± 28% | |
| oligodendrocyte precursor cell | 13 studies | 42% ± 17% | |
| microglial cell | 12 studies | 37% ± 11% | |
| macrophage | 11 studies | 40% ± 17% | |
| GABAergic neuron | 10 studies | 49% ± 23% | |
| pericyte | 10 studies | 33% ± 13% | |
| adipocyte | 9 studies | 41% ± 9% | |
| fibroblast | 9 studies | 28% ± 7% | |
| neuron | 6 studies | 40% ± 18% | |
| interneuron | 6 studies | 57% ± 23% | |
| T cell | 6 studies | 20% ± 4% | |
| retinal ganglion cell | 5 studies | 29% ± 16% | |
| monocyte | 5 studies | 28% ± 7% | |
| smooth muscle cell | 5 studies | 28% ± 6% | |
| granule cell | 4 studies | 34% ± 22% | |
| cardiac muscle cell | 4 studies | 25% ± 2% | |
| dendritic cell | 4 studies | 23% ± 3% | |
| mast cell | 4 studies | 21% ± 6% | |
| amacrine cell | 4 studies | 35% ± 14% | |
| retina horizontal cell | 4 studies | 46% ± 14% | |
| myeloid cell | 4 studies | 34% ± 6% | |
| GABAergic interneuron | 3 studies | 40% ± 11% | |
| progenitor cell | 3 studies | 32% ± 6% | |
| epithelial cell | 3 studies | 30% ± 19% | |
| CD8-positive, alpha-beta T cell | 3 studies | 21% ± 3% | |
| GABAergic amacrine cell | 3 studies | 32% ± 11% | |
| glycinergic amacrine cell | 3 studies | 34% ± 9% | |
| alveolar macrophage | 3 studies | 44% ± 13% | |
| natural killer cell | 3 studies | 21% ± 1% | |
| lymphocyte | 3 studies | 32% ± 16% | |
| leukocyte | 3 studies | 40% ± 11% | |
| mural cell | 3 studies | 32% ± 9% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 100% | 2928.44 | 2641 / 2642 | 100% | 10.41 | 705 / 705 |
| lung | 100% | 1437.69 | 577 / 578 | 100% | 4.62 | 1153 / 1155 |
| thymus | 100% | 1139.06 | 652 / 653 | 100% | 5.90 | 603 / 605 |
| breast | 100% | 1469.32 | 459 / 459 | 99% | 4.35 | 1111 / 1118 |
| bladder | 100% | 1012.62 | 21 / 21 | 99% | 4.04 | 500 / 504 |
| adrenal gland | 100% | 1732.40 | 258 / 258 | 99% | 5.37 | 228 / 230 |
| prostate | 100% | 940.36 | 244 / 245 | 99% | 3.50 | 497 / 502 |
| ovary | 100% | 1456.09 | 180 / 180 | 98% | 3.19 | 422 / 430 |
| kidney | 100% | 921.85 | 89 / 89 | 98% | 4.47 | 884 / 901 |
| uterus | 99% | 861.24 | 168 / 170 | 99% | 4.65 | 455 / 459 |
| skin | 99% | 940.08 | 1798 / 1809 | 98% | 5.95 | 463 / 472 |
| intestine | 100% | 815.05 | 962 / 966 | 96% | 3.14 | 508 / 527 |
| esophagus | 95% | 643.09 | 1375 / 1445 | 99% | 4.13 | 182 / 183 |
| stomach | 93% | 532.10 | 334 / 359 | 98% | 3.38 | 280 / 286 |
| pancreas | 73% | 326.72 | 238 / 328 | 97% | 4.35 | 173 / 178 |
| liver | 50% | 207.88 | 113 / 226 | 83% | 1.86 | 336 / 406 |
| adipose | 100% | 1834.90 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 1655.18 | 1335 / 1335 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 5.73 | 29 / 29 |
| spleen | 100% | 1845.18 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 3.54 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 1.82 | 1 / 1 |
| muscle | 99% | 812.87 | 794 / 803 | 0% | 0 | 0 / 0 |
| peripheral blood | 97% | 1358.65 | 904 / 929 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 96% | 4.38 | 77 / 80 |
| heart | 95% | 1155.74 | 820 / 861 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0006400 | Biological process | tRNA modification |
| GO_0006417 | Biological process | regulation of translation |
| GO_0005634 | Cellular component | nucleus |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0016438 | Molecular function | tRNA-queuosine(34) beta-mannosyltransferase activity |
| Gene name | GTDC1 |
| Protein name | Alternative protein GTDC1 Glycosyltransferase-like domain-containing protein 1 tRNA-queuosine alpha-mannosyltransferase (QTMAN) (EC 2.4.1.110) (Glycosyltransferase-like domain-containing protein 1) (Mannosyltransferase-like protein Xa) (Mat-Xa) |
| Synonyms | QTMAN |
| Description | FUNCTION: Glycosyltransferase that specifically catalyzes mannosylation of cytoplasmic tRNA(Asp) modified with queuosine at position 34 (queuosine(34)) . Mannosylates the cyclopentene moiety of queuosine(34) in tRNA(Asp) to form mannosyl-queuosine(34) . Mannosylation of queuosine(34) in tRNA(Asp) is required to slow-down elongation at cognate codons, GAC and GAU, thereby regulating protein translation . . |
| Accessions | ENST00000344850.8 [Q4AE62-1] F2Z2V8 ENST00000542155.5 [Q4AE62-1] ENST00000415569.5 B8ZZ45 ENST00000409214.5 [Q4AE62-1] ENST00000463875.6 [Q4AE62-6] C9JIH3 ENST00000392869.6 [Q4AE62-1] ENST00000618778.4 [Q4AE62-5] ENST00000392871.6 [Q4AE62-4] C9J2C5 Q4AE62 ENST00000392867.7 [Q4AE62-2] ENST00000682281.1 [Q4AE62-1] ENST00000417450.5 ENST00000437114.5 L0R871 ENST00000241391.9 [Q4AE62-4] ENST00000409298.5 |