I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| epithelial cell | 5 studies | 34% ± 14% | |
| ciliated cell | 3 studies | 25% ± 7% | |
| dendritic cell | 3 studies | 19% ± 4% | |
| goblet cell | 3 studies | 19% ± 2% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| epithelial cell | 5 studies | 34% ± 14% | |
| ciliated cell | 3 studies | 25% ± 7% | |
| dendritic cell | 3 studies | 19% ± 4% | |
| goblet cell | 3 studies | 19% ± 2% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| liver | 3 studies | 18% ± 2% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| prostate | 100% | 1054.69 | 245 / 245 | 100% | 22.99 | 502 / 502 |
| thymus | 100% | 929.57 | 653 / 653 | 100% | 11.40 | 604 / 605 |
| pancreas | 100% | 535.15 | 327 / 328 | 99% | 6.20 | 177 / 178 |
| breast | 100% | 829.11 | 458 / 459 | 99% | 10.97 | 1106 / 1118 |
| bladder | 100% | 554.14 | 21 / 21 | 98% | 8.52 | 494 / 504 |
| adrenal gland | 100% | 1602.24 | 258 / 258 | 97% | 7.38 | 224 / 230 |
| kidney | 100% | 961.06 | 89 / 89 | 97% | 6.85 | 877 / 901 |
| skin | 97% | 908.80 | 1761 / 1809 | 99% | 10.70 | 468 / 472 |
| liver | 100% | 4097.96 | 226 / 226 | 96% | 11.62 | 390 / 406 |
| uterus | 98% | 442.95 | 167 / 170 | 97% | 8.15 | 446 / 459 |
| brain | 95% | 527.80 | 2518 / 2642 | 100% | 8.44 | 705 / 705 |
| intestine | 98% | 631.67 | 946 / 966 | 97% | 6.53 | 511 / 527 |
| esophagus | 97% | 611.71 | 1402 / 1445 | 97% | 6.32 | 178 / 183 |
| stomach | 98% | 682.38 | 353 / 359 | 92% | 5.12 | 263 / 286 |
| ovary | 90% | 332.81 | 162 / 180 | 96% | 6.16 | 412 / 430 |
| lung | 88% | 402.38 | 509 / 578 | 98% | 7.56 | 1127 / 1155 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 19.98 | 29 / 29 |
| muscle | 100% | 1263.08 | 803 / 803 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 9.57 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 6.47 | 1 / 1 |
| spleen | 100% | 589.98 | 240 / 241 | 0% | 0 | 0 / 0 |
| adipose | 99% | 665.91 | 1191 / 1204 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 99% | 17.72 | 79 / 80 |
| blood vessel | 94% | 316.00 | 1258 / 1335 | 0% | 0 | 0 / 0 |
| heart | 85% | 311.93 | 728 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 73% | 519.46 | 682 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0006559 | Biological process | L-phenylalanine catabolic process |
| GO_0098869 | Biological process | cellular oxidant detoxification |
| GO_0006749 | Biological process | glutathione metabolic process |
| GO_0006572 | Biological process | tyrosine catabolic process |
| GO_0005829 | Cellular component | cytosol |
| GO_0005759 | Cellular component | mitochondrial matrix |
| GO_0005739 | Cellular component | mitochondrion |
| GO_0042803 | Molecular function | protein homodimerization activity |
| GO_0004602 | Molecular function | glutathione peroxidase activity |
| GO_0042802 | Molecular function | identical protein binding |
| GO_0005515 | Molecular function | protein binding |
| GO_0016034 | Molecular function | maleylacetoacetate isomerase activity |
| GO_0004364 | Molecular function | glutathione transferase activity |
| Gene name | GSTZ1 |
| Protein name | Glutathione S-transferase zeta 1 Maleylacetoacetate isomerase (MAAI) (EC 5.2.1.2) (GSTZ1-1) (Glutathione S-transferase zeta 1) (EC 2.5.1.18) maleylacetoacetate isomerase (EC 5.2.1.2) |
| Synonyms | hCG_22265 MAAI |
| Description | FUNCTION: Bifunctional enzyme showing minimal glutathione-conjugating activity with ethacrynic acid and 7-chloro-4-nitrobenz-2-oxa-1,3-diazole and maleylacetoacetate isomerase activity. Has also low glutathione peroxidase activity with T-butyl and cumene hydroperoxides. Is able to catalyze the glutathione dependent oxygenation of dichloroacetic acid to glyoxylic acid. . |
| Accessions | ENST00000557639.5 [O43708-2] G3V5U6 ENST00000557053.5 G3V267 G3V5T0 ENST00000216465.10 G3V3B9 ENST00000554279.5 ENST00000556627.5 ENST00000555583.1 A0A0A0MR33 ENST00000553586.5 ENST00000393734.5 [O43708-2] ENST00000361389.8 [O43708-2] ENST00000349555.7 G3V4T6 A0A0C4DFM0 ENST00000554846.5 O43708 G3V5G8 H0YJN8 ENST00000554381.1 |
