I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| enterocyte | 5 studies | 30% ± 10% | |
| epithelial cell | 4 studies | 30% ± 12% | |
| fibroblast | 3 studies | 25% ± 6% | |
| dendritic cell | 3 studies | 24% ± 6% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| enterocyte | 5 studies | 30% ± 10% | |
| epithelial cell | 4 studies | 30% ± 12% | |
| fibroblast | 3 studies | 25% ± 6% | |
| dendritic cell | 3 studies | 24% ± 6% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| intestine | 3 studies | 20% ± 1% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 100% | 1929.67 | 2635 / 2642 | 100% | 19.90 | 703 / 705 |
| skin | 99% | 1347.71 | 1796 / 1809 | 100% | 24.33 | 472 / 472 |
| thymus | 100% | 2638.80 | 653 / 653 | 99% | 18.88 | 596 / 605 |
| intestine | 100% | 3425.93 | 966 / 966 | 98% | 18.33 | 519 / 527 |
| kidney | 100% | 2605.78 | 89 / 89 | 98% | 17.68 | 887 / 901 |
| ovary | 100% | 3658.68 | 180 / 180 | 98% | 16.36 | 422 / 430 |
| stomach | 100% | 1744.66 | 359 / 359 | 98% | 25.05 | 279 / 286 |
| adrenal gland | 99% | 2138.05 | 255 / 258 | 97% | 12.91 | 224 / 230 |
| liver | 100% | 1741.22 | 225 / 226 | 96% | 16.69 | 390 / 406 |
| pancreas | 99% | 1151.97 | 324 / 328 | 94% | 15.67 | 167 / 178 |
| breast | 100% | 1801.10 | 459 / 459 | 92% | 15.04 | 1032 / 1118 |
| bladder | 100% | 2612.62 | 21 / 21 | 91% | 33.30 | 459 / 504 |
| esophagus | 100% | 2310.64 | 1443 / 1445 | 91% | 28.96 | 166 / 183 |
| lung | 98% | 1146.84 | 566 / 578 | 91% | 15.36 | 1049 / 1155 |
| prostate | 100% | 2244.24 | 245 / 245 | 86% | 7.86 | 431 / 502 |
| uterus | 100% | 1955.31 | 170 / 170 | 84% | 14.79 | 386 / 459 |
| eye | 0% | 0 | 0 / 0 | 100% | 33.50 | 80 / 80 |
| spleen | 100% | 2401.37 | 241 / 241 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 100% | 23.10 | 1 / 1 |
| muscle | 100% | 2422.63 | 802 / 803 | 0% | 0 | 0 / 0 |
| adipose | 100% | 1553.66 | 1202 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 1753.73 | 1332 / 1335 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 97% | 16.46 | 28 / 29 |
| heart | 97% | 1537.31 | 831 / 861 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 82% | 11.05 | 37 / 45 |
| peripheral blood | 67% | 680.43 | 619 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0042759 | Biological process | long-chain fatty acid biosynthetic process |
| GO_0042178 | Biological process | xenobiotic catabolic process |
| GO_0018916 | Biological process | nitrobenzene metabolic process |
| GO_0006749 | Biological process | glutathione metabolic process |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0005829 | Cellular component | cytosol |
| GO_0045171 | Cellular component | intercellular bridge |
| GO_0043295 | Molecular function | glutathione binding |
| GO_0019899 | Molecular function | enzyme binding |
| GO_0042803 | Molecular function | protein homodimerization activity |
| GO_0005515 | Molecular function | protein binding |
| GO_0004464 | Molecular function | leukotriene-C4 synthase activity |
| GO_0004364 | Molecular function | glutathione transferase activity |
| Gene name | GSTM4 |
| Protein name | Glutathione S-transferase (EC 2.5.1.18) Glutathione S-transferase Mu 4 (EC 2.5.1.18) (GST class-mu 4) (GST-Mu2) (GSTM4-4) (Leukotriene C4 synthase GSTM4) (EC 4.4.1.20) |
| Synonyms | |
| Description | FUNCTION: Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles . Catalyzes the conjugation of leukotriene A4 with reduced glutathione (GSH) to form leukotriene C4 . Can also catalyzes the transfer of a glutathionyl group from glutathione (GSH) to 13(S),14(S)-epoxy-docosahexaenoic acid to form maresin conjugate in tissue regeneration 1 (MCTR1), a bioactive lipid mediator that possess potent anti-inflammatory and proresolving actions . . |
| Accessions | ENST00000326729.9 [Q03013-2] ENST00000369836.9 [Q03013-1] A6NNT0 Q03013 ENST00000369833.5 |
