GSS report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006520Biological processamino acid metabolic process
GO_0046686Biological processresponse to cadmium ion
GO_0007399Biological processnervous system development
GO_0006979Biological processresponse to oxidative stress
GO_0006750Biological processglutathione biosynthetic process
GO_0070062Cellular componentextracellular exosome
GO_0005829Cellular componentcytosol
GO_0043295Molecular functionglutathione binding
GO_0042803Molecular functionprotein homodimerization activity
GO_0005524Molecular functionATP binding
GO_0042802Molecular functionidentical protein binding
GO_0005515Molecular functionprotein binding
GO_0004363Molecular functionglutathione synthase activity
GO_0000287Molecular functionmagnesium ion binding

IV. Literature review

[source]
Gene nameGSS
Protein nameGlutathione synthetase (GSH synthetase) (GSH-S) (EC 6.3.2.3) (Glutathione synthase)
Glutathione synthetase (GSH-S) (EC 6.3.2.3)
Glutathione synthetase (Glutathione synthase)
Glutathione synthetase
Glutathione synthetase (EC 6.3.2.3) (Glutathione synthase)
SynonymsHEL-S-88n
HEL-S-64p
DescriptionFUNCTION: Catalyzes the production of glutathione from gamma-glutamylcysteine and glycine in an ATP-dependent manner . Glutathione (gamma-glutamylcysteinylglycine, GSH) is the most abundant intracellular thiol in living aerobic cells and is required for numerous processes including the protection of cells against oxidative damage, amino acid transport, the detoxification of foreign compounds, the maintenance of protein sulfhydryl groups in a reduced state and acts as a cofactor for a number of enzymes . Participates in ophthalmate biosynthesis in hepatocytes (By similarity). .

AccessionsENST00000646735.1 [P48637-2]
P48637
ENST00000646766.1
A0A2R8Y430
V9HWJ1
ENST00000642493.1
A0A2R8Y4V9
A0A2R8Y6Y6
A0A2R8Y2F2
ENST00000644793.1 [P48637-1]
ENST00000644608.1
A0A2R8Y790
ENST00000645102.1
ENST00000642538.1
ENST00000643271.1
ENST00000643502.1
A0A2R8Y7I7
A0A2R8YF34
A0A2R8Y5T7
ENST00000645408.1
A0A0S2Z4J7
ENST00000646405.1
ENST00000643443.1
ENST00000643188.1 [P48637-1]
ENST00000645328.1
A0A2R8Y6Q7
ENST00000642498.1
A0A2R8Y446
ENST00000451957.2 [P48637-2]
A0A2R8Y2X9
ENST00000651619.1 [P48637-1]