Name | Number of supported studies | Average coverage | |
---|---|---|---|
ciliated cell | 8 studies | 27% ± 8% |
Insufficient scRNA-seq data for expression of GRIN3B at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
lung | 99% | 302.61 | 570 / 578 | 37% | 1.29 | 430 / 1155 |
kidney | 100% | 193.67 | 89 / 89 | 29% | 1.24 | 263 / 901 |
esophagus | 90% | 49.48 | 1297 / 1445 | 38% | 1.95 | 69 / 183 |
thymus | 100% | 202.22 | 653 / 653 | 27% | 0.57 | 166 / 605 |
ovary | 99% | 76.24 | 178 / 180 | 26% | 0.66 | 113 / 430 |
bladder | 100% | 60.48 | 21 / 21 | 17% | 0.40 | 85 / 504 |
uterus | 95% | 120.14 | 162 / 170 | 19% | 0.60 | 89 / 459 |
prostate | 98% | 91.59 | 240 / 245 | 5% | 0.14 | 27 / 502 |
skin | 95% | 85.85 | 1722 / 1809 | 5% | 0.09 | 24 / 472 |
intestine | 91% | 49.65 | 875 / 966 | 9% | 0.28 | 50 / 527 |
spleen | 100% | 170.87 | 240 / 241 | 0% | 0 | 0 / 0 |
breast | 94% | 70.82 | 433 / 459 | 4% | 0.08 | 48 / 1118 |
adipose | 93% | 51.08 | 1117 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 87% | 46.65 | 1162 / 1335 | 0% | 0 | 0 / 0 |
stomach | 76% | 30.37 | 272 / 359 | 9% | 0.39 | 26 / 286 |
pancreas | 65% | 24.04 | 213 / 328 | 20% | 0.45 | 35 / 178 |
peripheral blood | 81% | 38.81 | 748 / 929 | 0% | 0 | 0 / 0 |
brain | 66% | 54.12 | 1754 / 2642 | 11% | 0.21 | 81 / 705 |
heart | 70% | 28.07 | 605 / 861 | 0% | 0 | 0 / 0 |
adrenal gland | 53% | 16.26 | 136 / 258 | 13% | 0.43 | 31 / 230 |
liver | 62% | 21.79 | 139 / 226 | 4% | 0.13 | 16 / 406 |
muscle | 37% | 14.08 | 298 / 803 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 21% | 0.31 | 6 / 29 |
tonsil | 0% | 0 | 0 / 0 | 20% | 0.32 | 9 / 45 |
eye | 0% | 0 | 0 / 0 | 6% | 0.09 | 5 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0050804 | Biological process | modulation of chemical synaptic transmission |
GO_0051924 | Biological process | regulation of calcium ion transport |
GO_0035235 | Biological process | ionotropic glutamate receptor signaling pathway |
GO_0099505 | Biological process | regulation of presynaptic membrane potential |
GO_0060078 | Biological process | regulation of postsynaptic membrane potential |
GO_0051205 | Biological process | protein insertion into membrane |
GO_0070588 | Biological process | calcium ion transmembrane transport |
GO_0035249 | Biological process | synaptic transmission, glutamatergic |
GO_0098839 | Cellular component | postsynaptic density membrane |
GO_0005886 | Cellular component | plasma membrane |
GO_0043025 | Cellular component | neuronal cell body |
GO_0017146 | Cellular component | NMDA selective glutamate receptor complex |
GO_0008066 | Molecular function | glutamate receptor activity |
GO_1904315 | Molecular function | transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential |
GO_0004972 | Molecular function | NMDA glutamate receptor activity |
GO_0005261 | Molecular function | monoatomic cation channel activity |
GO_0030594 | Molecular function | neurotransmitter receptor activity |
GO_0016594 | Molecular function | glycine binding |
GO_0099507 | Molecular function | ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential |
GO_0005262 | Molecular function | calcium channel activity |
Gene name | GRIN3B |
Protein name | Glutamate receptor Glutamate receptor ionotropic, NMDA 3B (GluN3B) (N-methyl-D-aspartate receptor subtype 3B) (NMDAR3B) (NR3B) |
Synonyms | |
Description | FUNCTION: NMDA receptor subtype of glutamate-gated ion channels with reduced single-channel conductance, low calcium permeability and low voltage-dependent sensitivity to magnesium. Mediated by glycine. FUNCTION: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. . FUNCTION: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. . |
Accessions | Q5F0I5 O60391 ENST00000234389.3 Q5F0I4 |