GPAM report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0042104Biological processpositive regulation of activated T cell proliferation
GO_0055091Biological processphospholipid homeostasis
GO_0055089Biological processfatty acid homeostasis
GO_0006072Biological processglycerol-3-phosphate metabolic process
GO_0009749Biological processresponse to glucose
GO_0070236Biological processnegative regulation of activation-induced cell death of T cells
GO_0051607Biological processdefense response to virus
GO_0006631Biological processfatty acid metabolic process
GO_0016024Biological processCDP-diacylglycerol biosynthetic process
GO_0019432Biological processtriglyceride biosynthetic process
GO_0008654Biological processphospholipid biosynthetic process
GO_0006637Biological processacyl-CoA metabolic process
GO_0001817Biological processregulation of cytokine production
GO_0006924Biological processactivation-induced cell death of T cells
GO_0006651Biological processdiacylglycerol biosynthetic process
GO_0050798Biological processactivated T cell proliferation
GO_0006654Biological processphosphatidic acid biosynthetic process
GO_0006655Biological processphosphatidylglycerol biosynthetic process
GO_0040018Biological processpositive regulation of multicellular organism growth
GO_0005886Cellular componentplasma membrane
GO_0031966Cellular componentmitochondrial membrane
GO_0005741Cellular componentmitochondrial outer membrane
GO_0004366Molecular functionglycerol-3-phosphate O-acyltransferase activity
GO_0102420Molecular functionsn-1-glycerol-3-phosphate C16:0-DCA-CoA acyl transferase activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameGPAM
Protein nameGlycerol-3-phosphate acyltransferase 1, mitochondrial (EC 2.3.1.15)
Glycerol-3-phosphate acyltransferase 1, mitochondrial (GPAT-1) (EC 2.3.1.15)
SynonymsGPAT1
hCG_40975
KIAA1560
DescriptionFUNCTION: Esterifies acyl-group from acyl-ACP to the sn-1 position of glycerol-3-phosphate, an essential step in glycerolipids biosynthesis such as triglycerides, phosphatidic acids and lysophosphatidic acids. .

FUNCTION: Esterifies acyl-group from acyl-ACP to the sn-1 position of glycerol-3-phosphate, an essential step in glycerolipids biosynthesis such as triglycerides, phosphatidic acids and lysophosphatidic acids. .

FUNCTION: Esterifies acyl-group from acyl-ACP to the sn-1 position of glycerol-3-phosphate, an essential step in glycerolipids biosynthesis such as triglycerides, phosphatidic acids and lysophosphatidic acids. .

AccessionsQ9HCL2
Q5VW52
ENST00000348367.9
ENST00000369425.5
Q8N1G6