GP5 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of GP5 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of GP5 at tissue level.

III. Associated gene sets

GO_0007597Biological processblood coagulation, intrinsic pathway
GO_0010572Biological processpositive regulation of platelet activation
GO_0007155Biological processcell adhesion
GO_0007596Biological processblood coagulation
GO_0051209Biological processrelease of sequestered calcium ion into cytosol
GO_0035855Biological processmegakaryocyte development
GO_0070062Cellular componentextracellular exosome
GO_1990779Cellular componentglycoprotein Ib-IX-V complex
GO_0005886Cellular componentplasma membrane
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameGP5
Protein namePlatelet glycoprotein V (GPV) (Glycoprotein 5) (CD antigen CD42d)
Synonyms
DescriptionFUNCTION: The GPIb-V-IX complex functions as the vWF receptor and mediates vWF-dependent platelet adhesion to blood vessels. The adhesion of platelets to injured vascular surfaces in the arterial circulation is a critical initiating event in hemostasis.

AccessionsENST00000401815.1
ENST00000692618.1
P40197