I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| epithelial cell | 4 studies | 20% ± 6% | |
| astrocyte | 3 studies | 16% ± 2% | |
| glutamatergic neuron | 3 studies | 20% ± 3% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| epithelial cell | 4 studies | 20% ± 6% | |
| astrocyte | 3 studies | 16% ± 2% | |
| glutamatergic neuron | 3 studies | 20% ± 3% |
Insufficient scRNA-seq data for expression of GORASP1 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| bladder | 100% | 4768.10 | 21 / 21 | 100% | 29.57 | 504 / 504 |
| esophagus | 100% | 4493.89 | 1445 / 1445 | 100% | 19.16 | 183 / 183 |
| ovary | 100% | 3563.72 | 180 / 180 | 100% | 21.93 | 430 / 430 |
| pancreas | 100% | 3088.31 | 328 / 328 | 100% | 27.63 | 178 / 178 |
| prostate | 100% | 5457.12 | 245 / 245 | 100% | 36.79 | 502 / 502 |
| skin | 100% | 3671.99 | 1809 / 1809 | 100% | 30.67 | 472 / 472 |
| lung | 100% | 4795.00 | 578 / 578 | 100% | 21.04 | 1154 / 1155 |
| breast | 100% | 5047.71 | 459 / 459 | 100% | 30.85 | 1117 / 1118 |
| brain | 100% | 3474.71 | 2638 / 2642 | 100% | 46.25 | 705 / 705 |
| intestine | 100% | 5087.95 | 966 / 966 | 100% | 29.48 | 526 / 527 |
| stomach | 100% | 3865.52 | 359 / 359 | 100% | 26.49 | 285 / 286 |
| uterus | 100% | 4886.57 | 170 / 170 | 100% | 24.32 | 457 / 459 |
| kidney | 100% | 3915.38 | 89 / 89 | 99% | 19.94 | 896 / 901 |
| thymus | 100% | 5565.75 | 653 / 653 | 99% | 26.31 | 601 / 605 |
| liver | 100% | 2958.49 | 226 / 226 | 99% | 15.79 | 400 / 406 |
| adrenal gland | 100% | 3392.11 | 258 / 258 | 95% | 16.00 | 219 / 230 |
| adipose | 100% | 4301.86 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 4005.32 | 1335 / 1335 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 17.98 | 29 / 29 |
| spleen | 100% | 5099.11 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 20.20 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 20.60 | 1 / 1 |
| heart | 100% | 2845.74 | 859 / 861 | 0% | 0 | 0 / 0 |
| muscle | 100% | 2449.16 | 801 / 803 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 99% | 19.31 | 79 / 80 |
| peripheral blood | 95% | 1802.69 | 884 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0015031 | Biological process | protein transport |
| GO_0007030 | Biological process | Golgi organization |
| GO_0006487 | Biological process | protein N-linked glycosylation |
| GO_0061951 | Biological process | establishment of protein localization to plasma membrane |
| GO_0050774 | Biological process | negative regulation of dendrite morphogenesis |
| GO_0090161 | Biological process | Golgi ribbon formation |
| GO_0033116 | Cellular component | endoplasmic reticulum-Golgi intermediate compartment membrane |
| GO_0000139 | Cellular component | Golgi membrane |
| GO_0005801 | Cellular component | cis-Golgi network |
| GO_0005794 | Cellular component | Golgi apparatus |
| GO_0005515 | Molecular function | protein binding |
| GO_0046872 | Molecular function | metal ion binding |
| Gene name | GORASP1 |
| Protein name | Golgi reassembly-stacking protein 1 (Golgi peripheral membrane protein p65) (Golgi phosphoprotein 5) (GOLPH5) (Golgi reassembly-stacking protein of 65 kDa) (GRASP65) Golgi reassembly stacking protein 1 (cDNA FLJ58222, highly similar to Golgi reassembly-stacking protein 1) Golgi reassembly stacking protein 1 (cDNA FLJ32481 fis, clone SKNMC2001113, moderately similar to Golgi reassembly-stacking protein 1) Golgi reassembly stacking protein 1 |
| Synonyms | GRASP65 hCG_19028 GOLPH5 |
| Description | FUNCTION: Key structural protein of the Golgi apparatus . The membrane cisternae of the Golgi apparatus adhere to each other to form stacks, which are aligned side by side to form the Golgi ribbon . Acting in concert with GORASP2/GRASP55, is required for the formation and maintenance of the Golgi ribbon, and may be dispensable for the formation of stacks . However, other studies suggest that GORASP1 plays an important role in assembly and membrane stacking of the cisternae, and in the reassembly of Golgi stacks after breakdown during mitosis (By similarity). Caspase-mediated cleavage of GORASP1 is required for fragmentation of the Golgi during apoptosis (By similarity). Also mediates, via its interaction with GOLGA2/GM130, the docking of transport vesicles with the Golgi membranes . Mediates ER stress-induced unconventional (ER/Golgi-independent) trafficking of core-glycosylated CFTR to cell membrane . . |
| Accessions | ENST00000479927.6 A0A8Q3SHU6 ENST00000441081.2 ENST00000319283.8 [Q9BQQ3-1] ENST00000695442.1 ENST00000413243.4 A0A8Q3SHU9 ENST00000416741.6 A0A8Q3SI07 A0A8Q3SHV7 ENST00000695430.1 ENST00000695426.1 A0A8Q3SIN9 ENST00000493751.2 A0A8Q3WKF7 ENST00000411813.6 ENST00000695591.1 A0A8Q3WKH3 ENST00000695613.1 ENST00000493938.6 ENST00000695424.1 A0A8Q3SHQ3 ENST00000695425.1 A0A8Q3WL08 A0A8Q3SHR6 ENST00000695445.1 A0A8Q3WKI0 ENST00000437458.4 A0A8Q3SI18 ENST00000452389.7 [Q9BQQ3-2] A0A8Q3SHP4 ENST00000422110.7 C9J5S6 ENST00000695417.1 ENST00000695431.1 ENST00000695428.1 ENST00000453680.6 C9J0V5 ENST00000695595.1 A0A8Q3SHW7 H7C0J2 ENST00000695597.1 A0A8Q3WLK9 ENST00000419156.6 B4E1H8 ENST00000431601.6 [Q9BQQ3-3] A0A8Q3WKF9 ENST00000695412.1 A0A8Q3WKM5 C9J9V9 G3V0G1 ENST00000695414.1 Q9BQQ3 B3KPY8 A0A8Q3SHQ7 |
