Name | Number of supported studies | Average coverage | |
---|---|---|---|
fibroblast | 17 studies | 23% ± 10% | |
ciliated cell | 11 studies | 27% ± 11% | |
endothelial cell | 9 studies | 25% ± 8% | |
epithelial cell | 7 studies | 36% ± 21% | |
myofibroblast cell | 6 studies | 20% ± 3% | |
smooth muscle cell | 5 studies | 17% ± 2% | |
basal cell | 5 studies | 29% ± 8% | |
goblet cell | 5 studies | 34% ± 10% | |
type I pneumocyte | 4 studies | 21% ± 4% | |
club cell | 4 studies | 20% ± 4% | |
respiratory goblet cell | 4 studies | 26% ± 6% | |
secretory cell | 4 studies | 27% ± 8% | |
squamous epithelial cell | 4 studies | 34% ± 20% | |
classical monocyte | 4 studies | 20% ± 3% | |
abnormal cell | 4 studies | 19% ± 4% | |
glutamatergic neuron | 4 studies | 35% ± 19% | |
ionocyte | 3 studies | 23% ± 5% | |
pancreatic A cell | 3 studies | 41% ± 21% | |
type B pancreatic cell | 3 studies | 47% ± 21% | |
retinal bipolar neuron | 3 studies | 19% ± 4% | |
pericyte | 3 studies | 17% ± 2% | |
GABAergic neuron | 3 studies | 36% ± 12% | |
astrocyte | 3 studies | 24% ± 5% | |
oligodendrocyte precursor cell | 3 studies | 25% ± 7% | |
enteroendocrine cell | 3 studies | 21% ± 5% | |
connective tissue cell | 3 studies | 26% ± 8% | |
macrophage | 3 studies | 17% ± 1% | |
plasmacytoid dendritic cell | 3 studies | 24% ± 5% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
breast | 100% | 6595.18 | 459 / 459 | 100% | 66.92 | 1118 / 1118 |
esophagus | 100% | 6684.22 | 1445 / 1445 | 100% | 40.99 | 183 / 183 |
prostate | 100% | 7093.65 | 245 / 245 | 100% | 73.16 | 502 / 502 |
skin | 100% | 9113.07 | 1809 / 1809 | 100% | 51.06 | 472 / 472 |
stomach | 100% | 5189.45 | 359 / 359 | 100% | 35.37 | 285 / 286 |
adrenal gland | 100% | 5419.38 | 258 / 258 | 100% | 60.82 | 229 / 230 |
thymus | 100% | 7444.64 | 653 / 653 | 100% | 54.09 | 602 / 605 |
pancreas | 100% | 4770.23 | 328 / 328 | 99% | 51.86 | 177 / 178 |
intestine | 100% | 5768.64 | 966 / 966 | 99% | 38.26 | 524 / 527 |
bladder | 100% | 6084.52 | 21 / 21 | 99% | 43.96 | 501 / 504 |
lung | 100% | 6289.62 | 578 / 578 | 99% | 46.98 | 1148 / 1155 |
uterus | 100% | 6909.40 | 170 / 170 | 99% | 50.02 | 456 / 459 |
kidney | 100% | 4779.06 | 89 / 89 | 99% | 37.34 | 893 / 901 |
ovary | 100% | 6596.58 | 180 / 180 | 98% | 31.15 | 422 / 430 |
brain | 99% | 3972.39 | 2616 / 2642 | 99% | 34.82 | 698 / 705 |
liver | 100% | 3481.88 | 226 / 226 | 96% | 25.75 | 391 / 406 |
adipose | 100% | 6189.08 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 6673.44 | 1335 / 1335 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 100% | 44.95 | 80 / 80 |
spleen | 100% | 4416.51 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 45.36 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 31.61 | 1 / 1 |
muscle | 100% | 3984.64 | 799 / 803 | 0% | 0 | 0 / 0 |
heart | 98% | 4750.43 | 848 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 87% | 2435.16 | 805 / 929 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 86% | 17.95 | 25 / 29 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0090166 | Biological process | Golgi disassembly |
GO_0008356 | Biological process | asymmetric cell division |
GO_0007020 | Biological process | microtubule nucleation |
GO_0007098 | Biological process | centrosome cycle |
GO_0090307 | Biological process | mitotic spindle assembly |
GO_0007030 | Biological process | Golgi organization |
GO_0051225 | Biological process | spindle assembly |
GO_0060050 | Biological process | positive regulation of protein glycosylation |
GO_0010507 | Biological process | negative regulation of autophagy |
GO_0090306 | Biological process | meiotic spindle assembly |
GO_0015031 | Biological process | protein transport |
GO_0006888 | Biological process | endoplasmic reticulum to Golgi vesicle-mediated transport |
GO_0032091 | Biological process | negative regulation of protein binding |
GO_0090161 | Biological process | Golgi ribbon formation |
GO_0006486 | Biological process | protein glycosylation |
GO_0051289 | Biological process | protein homotetramerization |
GO_0005801 | Cellular component | cis-Golgi network |
GO_0005874 | Cellular component | microtubule |
GO_0000922 | Cellular component | spindle pole |
GO_0072686 | Cellular component | mitotic spindle |
GO_0000137 | Cellular component | Golgi cis cisterna |
GO_0005794 | Cellular component | Golgi apparatus |
GO_0033116 | Cellular component | endoplasmic reticulum-Golgi intermediate compartment membrane |
GO_0000139 | Cellular component | Golgi membrane |
GO_0030134 | Cellular component | COPII-coated ER to Golgi transport vesicle |
GO_0032580 | Cellular component | Golgi cisterna membrane |
GO_0019905 | Molecular function | syntaxin binding |
GO_0061676 | Molecular function | importin-alpha family protein binding |
GO_0045296 | Molecular function | cadherin binding |
GO_0019901 | Molecular function | protein kinase binding |
GO_0042802 | Molecular function | identical protein binding |
GO_0008017 | Molecular function | microtubule binding |
GO_0005515 | Molecular function | protein binding |
Gene name | GOLGA2 |
Protein name | Golgin subfamily A member 2 (130 kDa cis-Golgi matrix protein) (GM130) (GM130 autoantigen) (Golgin-95) Golgi matrix protein GM130 Golgin subfamily A member 2 Golgin A2 |
Synonyms | |
Description | FUNCTION: Peripheral membrane component of the cis-Golgi stack that acts as a membrane skeleton that maintains the structure of the Golgi apparatus, and as a vesicle thether that facilitates vesicle fusion to the Golgi membrane (Probable) . Required for normal protein transport from the endoplasmic reticulum to the Golgi apparatus and the cell membrane (By similarity). Together with p115/USO1 and STX5, involved in vesicle tethering and fusion at the cis-Golgi membrane to maintain the stacked and inter-connected structure of the Golgi apparatus. Plays a central role in mitotic Golgi disassembly: phosphorylation at Ser-37 by CDK1 at the onset of mitosis inhibits the interaction with p115/USO1, preventing tethering of COPI vesicles and thereby inhibiting transport through the Golgi apparatus during mitosis (By similarity). Also plays a key role in spindle pole assembly and centrosome organization . Promotes the mitotic spindle pole assembly by activating the spindle assembly factor TPX2 to nucleate microtubules around the Golgi and capture them to couple mitotic membranes to the spindle: upon phosphorylation at the onset of mitosis, GOLGA2 interacts with importin-alpha via the nuclear localization signal region, leading to recruit importin-alpha to the Golgi membranes and liberate the spindle assembly factor TPX2 from importin-alpha. TPX2 then activates AURKA kinase and stimulates local microtubule nucleation. Upon filament assembly, nascent microtubules are further captured by GOLGA2, thus linking Golgi membranes to the spindle . Regulates the meiotic spindle pole assembly, probably via the same mechanism (By similarity). Also regulates the centrosome organization . Also required for the Golgi ribbon formation and glycosylation of membrane and secretory proteins . . |
Accessions | ENST00000611957.5 B7ZC06 A0A8I5KYU9 ENST00000686884.1 ENST00000693185.1 ENST00000421699 A0A8I5KT73 ENST00000686291.1 ENST00000610329.5 A0A8J9BZL8 A0A1W2PQY5 ENST00000490628.3 ENST00000450617.8 ENST00000692923.1 A0A8I5KZ68 ENST00000693047.1 A0A8I5QL14 A0A8I5KQL3 Q08379 A0A8I5KRU0 ENST00000691841.1 ENST00000693180.1 A0A8I5KNZ1 R4GND7 ENST00000693736.1 H0Y7B8 ENST00000458730.3 ENST00000421699.8 [Q08379-1] A0A8I5KZ34 ENST00000685382.1 A0A6Q8KRG2 A0A8I5KUW5 A0A8I5KYB0 ENST00000639983.2 Q5PXD5 A0A8I5QJQ7 ENST00000685900.1 ENST00000687179.1 A0A087WYC0 |