GNRHR report

I. Expression across cell types

Insufficient scRNA-seq data for expression of GNRHR at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of GNRHR at tissue level.

III. Associated gene sets

GO_0097211Biological processcellular response to gonadotropin-releasing hormone
GO_0007186Biological processG protein-coupled receptor signaling pathway
GO_0032870Biological processcellular response to hormone stimulus
GO_0032274Biological processgonadotropin secretion
GO_0005886Cellular componentplasma membrane
GO_0016020Cellular componentmembrane
GO_0042277Molecular functionpeptide binding
GO_0004968Molecular functiongonadotropin-releasing hormone receptor activity

IV. Literature review

[source]
Gene nameGNRHR
Protein nameGonadotropin-releasing hormone receptor (GnRH receptor) (GnRH-R)
Gonadotropin-releasing hormone receptor
SynonymsGRHR
DescriptionFUNCTION: Receptor for gonadotropin releasing hormone (GnRH) that mediates the action of GnRH to stimulate the secretion of the gonadotropic hormones luteinizing hormone (LH) and follicle-stimulating hormone (FSH). This receptor mediates its action by association with G-proteins that activate a phosphatidylinositol-calcium second messenger system. Isoform 2 may act as an inhibitor of GnRH-R signaling.

AccessionsENST00000420975.2 [P30968-2]
ENST00000226413.5 [P30968-1]
V9GZN9
P30968
V9GZJ6