GNL2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0042254Biological processribosome biogenesis
GO_0008150Biological processbiological_process
GO_0005730Cellular componentnucleolus
GO_0016020Cellular componentmembrane
GO_0005634Cellular componentnucleus
GO_0005525Molecular functionGTP binding
GO_0003924Molecular functionGTPase activity
GO_0003723Molecular functionRNA binding

IV. Literature review

[source]
Gene nameGNL2
Protein nameG protein nucleolar 2
Nucleolar GTP-binding protein 2 (Autoantigen NGP-1)
Nucleolar GTP-binding protein 2
SynonymshCG_25676
NGP1
DescriptionFUNCTION: GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation . May promote cell proliferation possibly by increasing p53/TP53 protein levels, and consequently those of its downstream product CDKN1A/p21, and decreasing RPL23A protein levels . .

FUNCTION: GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. .

AccessionsQ5T0F3
ENST00000373062.8
ENST00000538069.2
Q13823
H0YG10