GMPR report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of GMPR at tissue level.

III. Associated gene sets

GO_0006144Biological processpurine nucleobase metabolic process
GO_0009409Biological processresponse to cold
GO_0006163Biological processpurine nucleotide metabolic process
GO_1902560Cellular componentGMP reductase complex
GO_0005829Cellular componentcytosol
GO_0003920Molecular functionGMP reductase activity
GO_0046872Molecular functionmetal ion binding

IV. Literature review

[source]
Gene nameGMPR
Protein nameGMP reductase 1 (GMPR 1) (EC 1.7.1.7) (Guanosine 5'-monophosphate oxidoreductase 1) (Guanosine monophosphate reductase 1)
GMP reductase (GMPR) (EC 1.7.1.7) (Guanosine 5'-monophosphate oxidoreductase) (Guanosine monophosphate reductase)
SynonymsGMPR1
DescriptionFUNCTION: Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. .

FUNCTION: Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. .

AccessionsENST00000259727.5
P36959
Q7Z527