Insufficient scRNA-seq data for expression of GMNC at single-cell level.
Insufficient scRNA-seq data for expression of GMNC at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
liver | 100% | 221.27 | 226 / 226 | 44% | 1.25 | 178 / 406 |
prostate | 54% | 14.61 | 132 / 245 | 48% | 2.87 | 239 / 502 |
kidney | 91% | 181.07 | 81 / 89 | 9% | 0.31 | 85 / 901 |
ovary | 25% | 9.18 | 45 / 180 | 70% | 14.45 | 301 / 430 |
pancreas | 74% | 29.32 | 244 / 328 | 2% | 0.06 | 4 / 178 |
uterus | 59% | 47.27 | 100 / 170 | 8% | 0.93 | 37 / 459 |
brain | 51% | 22.51 | 1346 / 2642 | 8% | 0.53 | 57 / 705 |
heart | 36% | 12.88 | 311 / 861 | 0% | 0 | 0 / 0 |
lung | 13% | 3.56 | 74 / 578 | 7% | 1.32 | 82 / 1155 |
breast | 12% | 2.13 | 56 / 459 | 0% | 0.01 | 3 / 1118 |
skin | 11% | 2.66 | 208 / 1809 | 0% | 0.00 | 1 / 472 |
esophagus | 8% | 1.07 | 116 / 1445 | 1% | 0.01 | 2 / 183 |
thymus | 3% | 0.43 | 20 / 653 | 5% | 0.19 | 32 / 605 |
intestine | 7% | 0.90 | 72 / 966 | 0% | 0.04 | 1 / 527 |
spleen | 6% | 0.85 | 14 / 241 | 0% | 0 | 0 / 0 |
stomach | 4% | 0.41 | 14 / 359 | 1% | 0.01 | 2 / 286 |
adrenal gland | 2% | 0.27 | 6 / 258 | 2% | 0.05 | 4 / 230 |
muscle | 3% | 0.41 | 24 / 803 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 2% | 0.04 | 1 / 45 |
bladder | 0% | 0 | 0 / 21 | 2% | 0.06 | 8 / 504 |
blood vessel | 1% | 0.20 | 19 / 1335 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 1% | 0.02 | 1 / 80 |
adipose | 1% | 0.16 | 13 / 1204 | 0% | 0 | 0 / 0 |
peripheral blood | 1% | 0.12 | 9 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0060271 | Biological process | cilium assembly |
GO_0008156 | Biological process | negative regulation of DNA replication |
GO_0045786 | Biological process | negative regulation of cell cycle |
GO_0006260 | Biological process | DNA replication |
GO_0005634 | Cellular component | nucleus |
GO_0005515 | Molecular function | protein binding |
GO_0003682 | Molecular function | chromatin binding |
Gene name | GMNC |
Protein name | Geminin coiled-coil domain containing (HCG1644800) Geminin coiled-coil domain-containing protein 1 |
Synonyms | hCG_1644800 GEMC1 |
Description | FUNCTION: Regulator of DNA replication. Promotes initiation of chromosomal DNA replication by mediating TOPBP1- and CDK2-dependent recruitment of CDC45L onto replication origins (By similarity). . |
Accessions | A6NCL1 G5E9I9 ENST00000456552.1 ENST00000442080.6 |