GLS2 | OmnibusX

Name	Number of supported studies	Average coverage
glutamatergic neuron	4 studies	43% ± 23%	Explore
GABAergic neuron	3 studies	39% ± 15%	Explore

Name	Number of supported studies	Average coverage
brain	3 studies	33% ± 17%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
liver	100%	628.55	226 / 226	21%	0.70	86 / 406
pancreas	100%	388.04	328 / 328	0%	0	0 / 178
brain	82%	189.83	2177 / 2642	1%	0.01	4 / 705
kidney	78%	27.12	69 / 89	1%	0.01	6 / 901
prostate	78%	33.72	190 / 245	0%	0.00	1 / 502
thymus	73%	24.78	478 / 653	0%	0.00	1 / 605
stomach	69%	31.04	247 / 359	2%	0.03	7 / 286
skin	71%	41.35	1280 / 1809	0%	0	0 / 472
ovary	68%	25.03	122 / 180	1%	0.02	6 / 430
uterus	63%	23.98	107 / 170	1%	0.01	4 / 459
bladder	52%	17.05	11 / 21	1%	0.02	7 / 504
spleen	49%	12.53	117 / 241	0%	0	0 / 0
esophagus	46%	19.54	668 / 1445	1%	0.02	2 / 183
lung	45%	14.47	261 / 578	1%	0.01	11 / 1155
breast	42%	14.57	195 / 459	1%	0.01	8 / 1118
adrenal gland	27%	7.83	70 / 258	11%	0.18	26 / 230
intestine	30%	8.57	287 / 966	2%	0.04	9 / 527
blood vessel	23%	6.11	310 / 1335	0%	0	0 / 0
peripheral blood	22%	13.28	200 / 929	0%	0	0 / 0
adipose	12%	3.06	149 / 1204	0%	0	0 / 0
tonsil	0%	0	0 / 0	7%	0.09	3 / 45
heart	4%	0.76	31 / 861	0%	0	0 / 0
muscle	0%	0.02	1 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
eye	0%	0	0 / 0	0%	0	0 / 80
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0042981	Biological process	regulation of apoptotic process
GO_0006537	Biological process	glutamate biosynthetic process
GO_0006543	Biological process	glutamine catabolic process
GO_0006520	Biological process	amino acid metabolic process
GO_0072593	Biological process	reactive oxygen species metabolic process
GO_0005739	Cellular component	mitochondrion
GO_0005759	Cellular component	mitochondrial matrix
GO_0004359	Molecular function	glutaminase activity
GO_0005515	Molecular function	protein binding

Gene name	GLS2
Protein name	Alternative protein GLS2 Truncated glutaminase 2 (EC 3.5.1.2) glutaminase (EC 3.5.1.2) Glutaminase 2 Glutaminase liver isoform, mitochondrial (GLS) (EC 3.5.1.2) (L-glutaminase) (L-glutamine amidohydrolase)
Synonyms	GA hCG_24976
Description	FUNCTION: Plays an important role in the regulation of glutamine catabolism. Promotes mitochondrial respiration and increases ATP generation in cells by catalyzing the synthesis of glutamate and alpha-ketoglutarate. Increases cellular anti-oxidant function via NADH and glutathione production. May play a role in preventing tumor proliferation. .
Accessions	ENST00000610413.4 F8WEU7 Q9UI32 Q0VD99 C9J3Q2 ENST00000461077.1 ENST00000486896.5 [Q9UI32-2] ENST00000486433.5 F8WBC9 ENST00000479952.5 F8WBL8 ENST00000483347.1 ENST00000424141.6 ENST00000311966.9 [Q9UI32-1] L0R6H3 G5E9X4 E5G744 A0A087X004 ENST00000623608.3 A8K0A6 ENST00000494474.5 ENST00000539272.5 E5G745 E5G743

GLS2 report