GLB1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_1904016Biological processresponse to Thyroglobulin triiodothyronine
GO_0005975Biological processcarbohydrate metabolic process
GO_0051413Biological processresponse to cortisone
GO_0019388Biological processgalactose catabolic process
GO_0046479Biological processglycosphingolipid catabolic process
GO_0030200Biological processheparan sulfate proteoglycan catabolic process
GO_0042340Biological processkeratan sulfate catabolic process
GO_0035578Cellular componentazurophil granule lumen
GO_0005576Cellular componentextracellular region
GO_0048471Cellular componentperinuclear region of cytoplasm
GO_0005773Cellular componentvacuole
GO_0070062Cellular componentextracellular exosome
GO_0005794Cellular componentGolgi apparatus
GO_1904813Cellular componentficolin-1-rich granule lumen
GO_0005737Cellular componentcytoplasm
GO_0043231Cellular componentintracellular membrane-bounded organelle
GO_0043202Cellular componentlysosomal lumen
GO_0042803Molecular functionprotein homodimerization activity
GO_0016936Molecular functiongalactoside binding
GO_0004565Molecular functionbeta-galactosidase activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameGLB1
Protein nameBeta-galactosidase (EC 3.2.1.23) (Acid beta-galactosidase) (Lactase) (Elastin receptor 1)
Galactosidase beta 1 (EC 3.2.1.23)
Galactosidase beta 1
Beta-galactosidase (EC 3.2.1.23) (Acid beta-galactosidase)
SynonymsELNR1
DescriptionFUNCTION: [Isoform 1]: Cleaves beta-linked terminal galactosyl residues from gangliosides, glycoproteins, and glycosaminoglycans. .; FUNCTION: [Isoform 2]: Has no beta-galactosidase catalytic activity, but plays functional roles in the formation of extracellular elastic fibers (elastogenesis) and in the development of connective tissue. Seems to be identical to the elastin-binding protein (EBP), a major component of the non-integrin cell surface receptor expressed on fibroblasts, smooth muscle cells, chondroblasts, leukocytes, and certain cancer cell types. In elastin producing cells, associates with tropoelastin intracellularly and functions as a recycling molecular chaperone which facilitates the secretions of tropoelastin and its assembly into elastic fibers. .

AccessionsENST00000415454.1
F4YK10
ENST00000399402.7
ENST00000438227.1
ENST00000436768.1
ENST00000440656.1
F8WEN1
ENST00000450835.1
ENST00000446732.5
ENST00000307363.10
C9JF15
C9J4G9
E7EQ29
ENST00000307377.12
P16278
C9J539
C9JWX1
F8WF40