GJD3 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of GJD3 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of GJD3 at tissue level.

III. Associated gene sets

GO_1901845Biological processnegative regulation of cell communication by electrical coupling involved in cardiac conduction
GO_0007154Biological processcell communication
GO_0034220Biological processmonoatomic ion transmembrane transport
GO_0086053Biological processAV node cell to bundle of His cell communication by electrical coupling
GO_0010459Biological processnegative regulation of heart rate
GO_0016264Biological processgap junction assembly
GO_0086065Biological processcell communication involved in cardiac conduction
GO_1903780Biological processnegative regulation of cardiac conduction
GO_0009749Biological processresponse to glucose
GO_0007267Biological processcell-cell signaling
GO_0009986Cellular componentcell surface
GO_0005922Cellular componentconnexin complex
GO_0005886Cellular componentplasma membrane
GO_0086075Molecular functiongap junction channel activity involved in cardiac conduction electrical coupling
GO_0005216Molecular functionmonoatomic ion channel activity
GO_0005515Molecular functionprotein binding
GO_0086077Molecular functiongap junction channel activity involved in AV node cell-bundle of His cell electrical coupling

IV. Literature review

[source]
Gene nameGJD3
Protein nameGap junction delta-3 protein (Connexin-31.9) (Cx31.9) (Gap junction alpha-11 protein) (Gap junction chi-1 protein)
SynonymsGJA11
GJC1
DescriptionFUNCTION: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. .

AccessionsQ8N144
ENST00000578689.2 [Q8N144-1]