GJA8 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of GJA8 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of GJA8 at tissue level.

III. Associated gene sets

GO_0002088Biological processlens development in camera-type eye
GO_0007267Biological processcell-cell signaling
GO_0032645Biological processregulation of granulocyte macrophage colony-stimulating factor production
GO_1990349Biological processgap junction-mediated intercellular transport
GO_0055085Biological processtransmembrane transport
GO_0005922Cellular componentconnexin complex
GO_0005886Cellular componentplasma membrane
GO_0005243Molecular functiongap junction channel activity
GO_0042802Molecular functionidentical protein binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameGJA8
Protein nameGap junction alpha-8 protein (Connexin-50) (Cx50) (Lens fiber protein MP70)
Gap junction alpha 8 protein
Gap junction alpha 8
Gap junction protein
Gap junction alpha 8 variant
SynonymsCXNL
DescriptionFUNCTION: Structural component of eye lens gap junctions . Gap junctions are dodecameric channels that connect the cytoplasm of adjoining cells. They are formed by the docking of two hexameric hemichannels, one from each cell membrane (By similarity). Small molecules and ions diffuse from one cell to a neighboring cell via the central pore . .

FUNCTION: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. .

FUNCTION: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. .

FUNCTION: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. .

FUNCTION: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. .

FUNCTION: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. .

FUNCTION: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. .

FUNCTION: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. .

FUNCTION: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. .

FUNCTION: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. .

FUNCTION: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. .

FUNCTION: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. .

FUNCTION: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. .

FUNCTION: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. .

FUNCTION: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. .

FUNCTION: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. .

AccessionsA0A097IW94
A0A097IWB1
A0A097IW70
A0A097IW99
P48165
A0A097IW93
A0A097IW74
A0A097IW59
A0A097IW49
X5D7G1
A0A097IWA4
A0A097IW90
A0A097IWA1
A0A097IW98
A0A097IWA5
ENST00000369235.2
A0A2I6SQQ9
A0A0U3E7C9
A0A097IW54
A0A097IW80