GINS3 | OmnibusX

Name	Number of supported studies	Average coverage
astrocyte	5 studies	42% ± 18%	Explore
Schwann cell	3 studies	34% ± 9%	Explore
oligodendrocyte precursor cell	3 studies	32% ± 18%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of GINS3 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
breast	100%	347.39	458 / 459	97%	5.82	1087 / 1118
esophagus	100%	467.81	1439 / 1445	97%	7.70	178 / 183
uterus	98%	272.11	166 / 170	98%	12.27	452 / 459
adrenal gland	100%	662.79	257 / 258	96%	7.58	220 / 230
skin	100%	413.82	1805 / 1809	95%	6.10	450 / 472
brain	97%	379.52	2560 / 2642	98%	9.77	688 / 705
intestine	100%	431.23	963 / 966	95%	6.31	499 / 527
bladder	95%	207.95	20 / 21	96%	7.07	483 / 504
stomach	97%	200.09	348 / 359	94%	5.60	268 / 286
lung	88%	192.16	509 / 578	91%	6.74	1051 / 1155
thymus	99%	208.65	645 / 653	80%	3.76	485 / 605
ovary	69%	86.88	125 / 180	93%	4.76	402 / 430
prostate	99%	241.04	242 / 245	56%	1.59	283 / 502
kidney	90%	152.22	80 / 89	64%	2.11	576 / 901
pancreas	51%	57.86	167 / 328	66%	2.50	118 / 178
lymph node	0%	0	0 / 0	100%	12.08	29 / 29
spleen	100%	558.64	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	13.37	45 / 45
ureter	0%	0	0 / 0	100%	2.49	1 / 1
adipose	100%	395.17	1201 / 1204	0%	0	0 / 0
heart	99%	342.09	849 / 861	0%	0	0 / 0
liver	49%	65.85	110 / 226	42%	1.91	169 / 406
eye	0%	0	0 / 0	78%	2.80	62 / 80
blood vessel	58%	87.47	779 / 1335	0%	0	0 / 0
muscle	55%	74.72	440 / 803	0%	0	0 / 0
peripheral blood	36%	242.90	334 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

GO_1902975	Biological process	mitotic DNA replication initiation
GO_0006268	Biological process	DNA unwinding involved in DNA replication
GO_0000811	Cellular component	GINS complex
GO_0071162	Cellular component	CMG complex
GO_0005654	Cellular component	nucleoplasm
GO_0005634	Cellular component	nucleus
GO_0005515	Molecular function	protein binding

Gene name	GINS3
Protein name	DNA replication complex GINS protein PSF3 (GINS complex subunit 3) Alternative protein GINS3 GINS complex subunit 3 isoform 3 DNA replication complex GINS protein PSF3
Synonyms	PSF3
Description	FUNCTION: Required for correct functioning of the GINS complex, a complex that plays an essential role in the initiation of DNA replication, and progression of DNA replication forks . GINS complex is a core component of CDC45-MCM-GINS (CMG) helicase, the molecular machine that unwinds template DNA during replication, and around which the replisome is built . . FUNCTION: The GINS complex plays an essential role in the initiation of DNA replication. . FUNCTION: The GINS complex plays an essential role in the initiation of DNA replication. . FUNCTION: The GINS complex plays an essential role in the initiation of DNA replication. .
Accessions	A0A0S2Z5L4 A0A0S2Z5L0 A0A0S2Z5L3 L8E887 ENST00000318129.6 [Q9BRX5-1] ENST00000328514.11 [Q9BRX5-2] A0A0S2Z5P2 Q9BRX5 ENST00000426538.6 [Q9BRX5-3]

GINS3 report