I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| glutamatergic neuron | 3 studies | 18% ± 3% | |
| transit amplifying cell | 3 studies | 36% ± 14% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| glutamatergic neuron | 3 studies | 18% ± 3% | |
| transit amplifying cell | 3 studies | 36% ± 14% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| liver | 3 studies | 18% ± 2% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| skin | 99% | 464.82 | 1796 / 1809 | 93% | 15.97 | 439 / 472 |
| uterus | 82% | 86.79 | 139 / 170 | 99% | 33.88 | 454 / 459 |
| ovary | 82% | 93.87 | 147 / 180 | 98% | 17.07 | 420 / 430 |
| brain | 93% | 180.09 | 2461 / 2642 | 80% | 12.27 | 566 / 705 |
| intestine | 76% | 170.96 | 733 / 966 | 95% | 23.39 | 503 / 527 |
| breast | 70% | 73.30 | 321 / 459 | 95% | 17.83 | 1059 / 1118 |
| stomach | 69% | 123.19 | 246 / 359 | 95% | 22.49 | 272 / 286 |
| bladder | 67% | 54.76 | 14 / 21 | 95% | 24.36 | 481 / 504 |
| esophagus | 57% | 249.08 | 826 / 1445 | 99% | 22.12 | 181 / 183 |
| lung | 61% | 83.64 | 351 / 578 | 90% | 19.26 | 1040 / 1155 |
| kidney | 87% | 127.12 | 77 / 89 | 44% | 3.14 | 400 / 901 |
| adrenal gland | 90% | 108.34 | 232 / 258 | 20% | 2.30 | 45 / 230 |
| liver | 52% | 67.17 | 117 / 226 | 55% | 6.53 | 222 / 406 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 20.79 | 29 / 29 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 38.77 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 11.39 | 1 / 1 |
| prostate | 83% | 86.38 | 203 / 245 | 17% | 1.19 | 83 / 502 |
| spleen | 99% | 245.41 | 238 / 241 | 0% | 0 | 0 / 0 |
| pancreas | 37% | 27.29 | 121 / 328 | 58% | 5.96 | 103 / 178 |
| thymus | 59% | 44.59 | 385 / 653 | 25% | 2.98 | 152 / 605 |
| adipose | 60% | 54.22 | 718 / 1204 | 0% | 0 | 0 / 0 |
| peripheral blood | 47% | 613.61 | 435 / 929 | 0% | 0 | 0 / 0 |
| blood vessel | 32% | 23.07 | 424 / 1335 | 0% | 0 | 0 / 0 |
| heart | 23% | 17.02 | 201 / 861 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 18% | 0.95 | 14 / 80 |
| muscle | 3% | 1.79 | 25 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0001833 | Biological process | inner cell mass cell proliferation |
| GO_1902983 | Biological process | DNA strand elongation involved in mitotic DNA replication |
| GO_0006268 | Biological process | DNA unwinding involved in DNA replication |
| GO_0000811 | Cellular component | GINS complex |
| GO_0071162 | Cellular component | CMG complex |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0005634 | Cellular component | nucleus |
| GO_0005515 | Molecular function | protein binding |
| Gene name | GINS1 |
| Protein name | DNA replication complex GINS protein PSF1 (GINS complex subunit 1) Alternative protein GINS1 DNA replication complex GINS protein PSF1 GINS complex subunit 1 |
| Synonyms | KIAA0186 PSF1 |
| Description | FUNCTION: Required for correct functioning of the GINS complex, a complex that plays an essential role in the initiation of DNA replication, and progression of DNA replication forks . GINS complex is a core component of CDC45-MCM-GINS (CMG) helicase, the molecular machine that unwinds template DNA during replication, and around which the replisome is built . . FUNCTION: Required for correct functioning of the GINS complex, a complex that plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex is a core component of CDC45-MCM-GINS (CMG) helicase, the molecular machine that unwinds template DNA during replication, and around which the replisome is built. . FUNCTION: Required for correct functioning of the GINS complex, a complex that plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex is a core component of CDC45-MCM-GINS (CMG) helicase, the molecular machine that unwinds template DNA during replication, and around which the replisome is built. . FUNCTION: Required for correct functioning of the GINS complex, a complex that plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex is a core component of CDC45-MCM-GINS (CMG) helicase, the molecular machine that unwinds template DNA during replication, and around which the replisome is built. . FUNCTION: Required for correct functioning of the GINS complex, a complex that plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex is a core component of CDC45-MCM-GINS (CMG) helicase, the molecular machine that unwinds template DNA during replication, and around which the replisome is built. . FUNCTION: Required for correct functioning of the GINS complex, a complex that plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex is a core component of CDC45-MCM-GINS (CMG) helicase, the molecular machine that unwinds template DNA during replication, and around which the replisome is built. . FUNCTION: Required for correct functioning of the GINS complex, a complex that plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex is a core component of CDC45-MCM-GINS (CMG) helicase, the molecular machine that unwinds template DNA during replication, and around which the replisome is built. . FUNCTION: Required for correct functioning of the GINS complex, a complex that plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex is a core component of CDC45-MCM-GINS (CMG) helicase, the molecular machine that unwinds template DNA during replication, and around which the replisome is built. . FUNCTION: Required for correct functioning of the GINS complex, a complex that plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex is a core component of CDC45-MCM-GINS (CMG) helicase, the molecular machine that unwinds template DNA during replication, and around which the replisome is built. . FUNCTION: Required for correct functioning of the GINS complex, a complex that plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex is a core component of CDC45-MCM-GINS (CMG) helicase, the molecular machine that unwinds template DNA during replication, and around which the replisome is built. . FUNCTION: Required for correct functioning of the GINS complex, a complex that plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex is a core component of CDC45-MCM-GINS (CMG) helicase, the molecular machine that unwinds template DNA during replication, and around which the replisome is built. . FUNCTION: Required for correct functioning of the GINS complex, a complex that plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex is a core component of CDC45-MCM-GINS (CMG) helicase, the molecular machine that unwinds template DNA during replication, and around which the replisome is built. . FUNCTION: Required for correct functioning of the GINS complex, a complex that plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex is a core component of CDC45-MCM-GINS (CMG) helicase, the molecular machine that unwinds template DNA during replication, and around which the replisome is built. . |
| Accessions | ENST00000696793.1 ENST00000696875.1 A0A8Q3WLM7 A0A8Q3SIY5 A0A8Q3WM37 ENST00000696814.1 A0A8Q3WLP3 ENST00000696876.1 ENST00000696804.1 A0A8Q3SIW3 A0A8Q3WMM5 A0A8Q3WLL0 ENST00000262460.5 ENST00000696896.1 ENST00000696895.1 A0A8Q3SJ38 A0A8Q3WMG9 ENST00000696894.1 ENST00000696810.1 A0A8Q3SJK6 Q14691 ENST00000696870.1 ENST00000696874.1 A0A8Q3SJ10 A0A8Q3WLL7 ENST00000696807.1 ENST00000696806.1 ENST00000696862.1 ENST00000484893.2 A0A8Q3WLJ3 A0A8Q3WLK7 L8ECJ2 ENST00000696878.1 |
