GHRH report

I. Expression across cell types

Insufficient scRNA-seq data for expression of GHRH at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of GHRH at tissue level.

III. Associated gene sets

GO_0060124Biological processpositive regulation of growth hormone secretion
GO_0021984Biological processadenohypophysis development
GO_0046005Biological processpositive regulation of circadian sleep/wake cycle, REM sleep
GO_0030252Biological processgrowth hormone secretion
GO_0032880Biological processregulation of protein localization
GO_0035264Biological processmulticellular organism growth
GO_0007267Biological processcell-cell signaling
GO_0043568Biological processpositive regulation of insulin-like growth factor receptor signaling pathway
GO_0007189Biological processadenylate cyclase-activating G protein-coupled receptor signaling pathway
GO_0008284Biological processpositive regulation of cell population proliferation
GO_0032094Biological processresponse to food
GO_0040018Biological processpositive regulation of multicellular organism growth
GO_0005615Cellular componentextracellular space
GO_0005576Cellular componentextracellular region
GO_0043204Cellular componentperikaryon
GO_0043195Cellular componentterminal bouton
GO_0051428Molecular functionpeptide hormone receptor binding
GO_0031770Molecular functiongrowth hormone-releasing hormone receptor binding
GO_0016608Molecular functiongrowth hormone-releasing hormone activity
GO_0005184Molecular functionneuropeptide hormone activity

IV. Literature review

[source]
Gene nameGHRH
Protein nameSomatoliberin (Growth hormone-releasing factor) (GRF) (Growth hormone-releasing hormone) (GHRH) (Somatocrinin) (Somatorelin) (Sermorelin)
SynonymsGHRF
DescriptionFUNCTION: GRF is released by the hypothalamus and acts on the adenohypophyse to stimulate the secretion of growth hormone.

AccessionsENST00000373614.7 [P01286-1]
ENST00000709405.1 [P01286-1]
ENST00000237527.8 [P01286-2]
ENST00000709406.1 [P01286-2]
P01286