Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| endothelial cell | 7 studies | 23% ± 7% | |
| epithelial cell | 4 studies | 35% ± 12% | |
| GABAergic neuron | 4 studies | 30% ± 15% | |
| glutamatergic neuron | 4 studies | 38% ± 18% | |
| dendritic cell | 3 studies | 17% ± 3% | |
| goblet cell | 3 studies | 21% ± 5% | |
| neuron | 3 studies | 30% ± 10% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 3 studies | 32% ± 12% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| breast | 100% | 1617.88 | 459 / 459 | 100% | 30.64 | 1118 / 1118 |
| esophagus | 100% | 1493.34 | 1445 / 1445 | 100% | 12.33 | 183 / 183 |
| prostate | 100% | 2010.37 | 245 / 245 | 100% | 24.83 | 502 / 502 |
| thymus | 100% | 1623.84 | 653 / 653 | 100% | 15.94 | 605 / 605 |
| uterus | 100% | 1486.34 | 170 / 170 | 100% | 14.69 | 459 / 459 |
| brain | 100% | 1384.36 | 2639 / 2642 | 100% | 15.23 | 705 / 705 |
| lung | 100% | 1351.88 | 577 / 578 | 100% | 14.17 | 1155 / 1155 |
| ovary | 100% | 1351.99 | 180 / 180 | 100% | 15.65 | 429 / 430 |
| adrenal gland | 100% | 1655.74 | 258 / 258 | 100% | 13.82 | 229 / 230 |
| kidney | 100% | 1514.54 | 89 / 89 | 100% | 10.18 | 897 / 901 |
| pancreas | 100% | 657.97 | 328 / 328 | 99% | 13.50 | 177 / 178 |
| bladder | 100% | 1562.95 | 21 / 21 | 99% | 13.02 | 499 / 504 |
| stomach | 100% | 1179.31 | 359 / 359 | 99% | 11.36 | 282 / 286 |
| skin | 100% | 1462.86 | 1808 / 1809 | 98% | 13.91 | 464 / 472 |
| liver | 100% | 549.55 | 226 / 226 | 98% | 9.12 | 397 / 406 |
| intestine | 100% | 1613.05 | 966 / 966 | 98% | 11.97 | 514 / 527 |
| adipose | 100% | 1538.66 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 1364.32 | 1335 / 1335 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 9.12 | 29 / 29 |
| muscle | 100% | 1181.55 | 803 / 803 | 0% | 0 | 0 / 0 |
| spleen | 100% | 1335.30 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 9.75 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 16.51 | 1 / 1 |
| heart | 99% | 1073.60 | 851 / 861 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 95% | 8.18 | 76 / 80 |
| peripheral blood | 92% | 779.32 | 851 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0008299 | Biological process | isoprenoid biosynthetic process |
| GO_0006720 | Biological process | isoprenoid metabolic process |
| GO_0045337 | Biological process | farnesyl diphosphate biosynthetic process |
| GO_0033384 | Biological process | geranyl diphosphate biosynthetic process |
| GO_0033386 | Biological process | geranylgeranyl diphosphate biosynthetic process |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0005829 | Cellular component | cytosol |
| GO_0030018 | Cellular component | Z disc |
| GO_0048471 | Cellular component | perinuclear region of cytoplasm |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0004161 | Molecular function | dimethylallyltranstransferase activity |
| GO_0004337 | Molecular function | geranyltranstransferase activity |
| GO_0005515 | Molecular function | protein binding |
| GO_0004311 | Molecular function | farnesyltranstransferase activity |
| GO_0004659 | Molecular function | prenyltransferase activity |
| GO_0046872 | Molecular function | metal ion binding |
| GO_0042802 | Molecular function | identical protein binding |
| Gene name | GGPS1 |
| Protein name | Geranylgeranyl diphosphate synthase 1 Geranylgeranyl pyrophosphate synthase (GGPP synthase) (GGPPSase) (EC 2.5.1.-) ((2E,6E)-farnesyl diphosphate synthase) (Dimethylallyltranstransferase) (EC 2.5.1.1) (Farnesyl diphosphate synthase) (Farnesyltranstransferase) (EC 2.5.1.29) (Geranylgeranyl diphosphate synthase) (Geranyltranstransferase) (EC 2.5.1.10) |
| Synonyms | |
| Description | FUNCTION: Catalyzes the trans-addition of the three molecules of IPP onto DMAPP to form geranylgeranyl pyrophosphate, an important precursor of carotenoids and geranylated proteins. . |
| Accessions | ENST00000471812.5 ENST00000488594.5 [O95749-1] ENST00000282841.9 [O95749-1] C9J7M1 ENST00000358966.6 [O95749-1] ENST00000391855.2 [O95749-2] O95749 ENST00000497327.1 C9J6G3 |